Do you want to contribute to improving human health?

At the Department of Oncology-Pathology basic, translational and clinical research and educational activities related to cancer is carried out. Approximately 300 people from over 40 nations are currently working at the department. About 30 research groups with various cancer research profiles are involved and we have around 110 PhD students. The Department of Oncology-Pathology is responsible for undergraduate courses in Pathology, Oncology and Forensic Medicine for medical students, as well as for Tumor biology courses for biomedicine students and Pathology courses for opticians.

Your mission

We search for a highly motivated postdoctoral researcher in bioinformatics to join a consortium of three research teams dedicated to understand the function of 3D epigenome folding and its deregulation in human diseases from entirely novel perspectives. The candidate is expected to drive a postdoctoral project and participate in collaborative efforts to uncover hitherto unknown therapeutic targets in complex diseases, such as cancer and diabetes. The work will be carried out in the lab of Associate professor Anita Göndör who has innovated state-of-the-art techniques enabling the analysis of 3D chromatin structures and chromatin fibre networks in single cells and small cell populations to provide unique opportunities for novel discoveries.

Model systems are exclusively based on human cells and unique, well-characterized patient material, such liquid and solid tumors as well as muscle and adipose tissue. The successful candidate will join the group consisting of 9 postdocs, 4 PhD students and four affiliated scientists.

For further information about our work, please consult the following recent publications and websites: CD Mallet de Lima and Göndör A. Science 2018 Mar 16; 359(6381):1212-1213; Zhao et al, Mol Cell 59:984-97 (2015); Feinberg, Koldobiskiy and Göndör, Nature Review Genetics 17:284-99 (2016); Göndör and Ohlsson, Nature 2009

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

To be eligible for a postdoctoral position in bioinformatics, is one who has obtained a PhD or equivalent in Computational Biology, Computer Engineering, or a relevant quantitative scientific discipline. In addition, the successful candidate must have:

  • Experience in the analysis of NGS data, in particular: Circadian RNA-seq, single cell RNA-seq, ChIP-seq, 3C-based chromatin interactome datasets
  • Experience in network analysis
  • Experience in Pathway analyses
  • Excellent knowledge in biostatistics
  • Extensive experience in using R/BioConductor, Unix/Linux environment (prior scripting language experience e.g. Python/Perl)
  • Experience in data visualization including computer simulations
  • Experience in meta-analysis
  • Experience in SNP calling from NGS data
  • Proficiency in written and spoken English
  • Good understanding of biological concepts and/or willingness to learn
  • Experience in working with wet lab scientists

A high level of organizational and communication skills, as well as an ability to independently perform experiments and implement interpretation of data, is mandatory. 

What do we offer?

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.

This is a temporary position starting with one year, with a possibility of prolongation.

Location: Solna

Anita Göndör's Group

Application

An employment application must contain the following documents in English or Swedish:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

Welcome to apply at the latest 2021-01-20. 

The application is to be submitted through the Varbi recruitment system.

 

Want to make a difference? Join us and contribute to better health for all

Type of employment Temporary position longer than 6 months
Contract type Full time
First day of employment As per agreement
Number of positions 1
Working hours 100%
City Stockholm
County Stockholms län
Country Sweden
Reference number STÖD 2-63/2021
Contact
  • Anita Göndör, anita.gondor@ki.se
Union representative
  • Helen Eriksson, OFR, 08-524 823 38
  • Andreas Lundqvist, SACO, 08-517 768 84
Published 07.Jan.2021
Last application date 20.Jan.2021 11:59 PM CET

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