Do you want to contribute to top quality medical research?

HTGE/KGE is seeking to recruit a research engineer to support our team for a duration of 12 months in the first instance, with a possible extension to a maximum of 24 months in total.

HTGE is a national SciLifeLab facility based at the Department of Medical Biochemistry and Biophysics in Biomedicum, Solna. HTGE’s mission is to provide pooled CRISPR-Cas9 genetic screening to the Swedish research community, and to develop novel, cutting-edge research tools based on CRISPR-Cas9 technology. KGE, our second branch, is a Karolinska core facility providing services in precision genome editing in cell lines.

Your mission

The successful candidate will contribute experimental support to pooled, genome-wide CRISPR-Cas9 screens and the creation of precision edits in cell line using CRISPR-Cas9. Your main tasks will be large-scale cell culture, molecular biology work such as molecular cloning, genomic DNA preparation, NGS library preparation, protocol optimization, allele quantification by droplet digital PCR, genotyping, etc, as well as performing other general laboratory duties.

Your profile

Applicants should have postdoctoral research experience or equivalent qualifications. Strong, demonstrable laboratory skills are essential. We expect proficiency in standard mammalian cell culture, as well as excellent time- and project management skills: You are able to multi-task and manage and handle a large number of projects in parallel. Previous practical experience with CRISPR-Cas9 technology, in particular gene knock-out and creation of reporter cell lines by CRISPR-Cas is a requirement. We value a positive, proactive attitude, good communication skills and the ability to carry out assigned tasks meticulously and in a timely fashion. Candidates are required to be fluent in English.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Location: Biomedicum, Solna/Stockholm

More information:


The application must contain the following documents in English:

  1. A personal letter explaining how the applicant’s profile and work experience matches the job requirements.
  2. A complete curriculum vitae without gaps, including education, previous positions, any leave of absence; as well as a short summary of current work (no more than one page).
  3. The contact details of at least two referees.
  4. A complete list of publications.

Welcome to apply at the latest 6th of July

The application is to be submitted through the Varbi recruitment system.  

Want to make a difference? Join us and contribute to better health for all

Type of employment Temporary position longer than 6 months
Contract type Full time
First day of employment Upon agreement
Salary Monthly salary
Number of positions 1
Working hours 100 %
City Stockholm
County Stockholms län
Country Sweden
Reference number 2-2844/2020
  • Bernhard Schmierer,
Union representative
  • Venus Azhary, OFR, 0707-124 127
Published 23.Jun.2020
Last application date 06.Jul.2020 11:59 PM CET

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