The Department of Biosciences and Nutrition performs research and education in several areas of medical science including bioorganic chemistry, molecular endocrinology, cancer biology, functional genomics, systems biology, epigenetics, structural biochemistry, cellular virology, and nutrition. It offers an excellent international research and working environment, including around 250 scientists, students, administrative and technical personnel. The Department resides in the new biomedical research building Neo, aimed at being a creative and open environment that enables meetings, synergies, and exploration of areas of mutual interest across disciplines.

Your mission

We are looking for a Postdoc to Rune Toftgård´s research group.The group studies the genetic and molecular mechanisms of Hedgehog signalling and the importance of this signalling pathway in cancer development with a particular interest in strategies for therapeutic intervention.

The successful applicant will perform studies on pharmacological modulation of Hedgehog signalling at the level of the GLI transcription factors aiming at the characterization of the molecular target for the small molecule inhibitor GANT61 previously described by our laboratory.

This position is a temporary employment for 6 months.


We are looking for goal-oriented candidates with demonstrated experience in cell- and molecular biology and biochemistry.  
The candidate should be able to interact closely with the supervisor but at the same time be able to independently progress the project. Strong communication skills and English proficiency, both written and spoken, are required. Background knowledge about the Hedgehog signalling pathway and experience with the Cellular Thermal Shift Assay (CETSA) is an advantage.  Emphasis will be placed on personal suitability.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Location: Flemingsberg 


An employment application must contain the following documents in English or Swedish:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

Welcome to apply at the latest 14 July 2020.

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Type of employment Temporary position 3-6 months
Contract type Full time
Number of positions 1
Working hours 100 %
City Huddinge
County Stockholms län
Country Sweden
Reference number 2-2662/2020
  • Rune Toftgård, +46-8-524 810 53
  • Thomas Tinglöv, Head of Administration, +46-8-524 835 49
Union representative
  • Anders Lindholm. OFR, +46-8-524 810 12
  • Henry Wölling, SEKO, +46-8-524 840 80
  • Chandrashekar Bangalore Revanna, SACO, +46-73-083 98 85
Published 29.Jun.2020
Last application date 14.Jul.2020 11:59 PM CET

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