Do you want to contribute to improving human health?

Ana Mendanha Falcão has recently established her research group, which is focusing on the role of the choroid plexus in diseases such as multiple sclerosis. Her team aims to investigate the choroid plexus as a source of biologically active molecules to the central nervous system, in order to influence disease dynamics. The choroid plexus will be studied as an alternative target for disease therapies since it can be modulated by peripheral blood and it can substantially alter the brain composition both in terms of biologically active molecules and immune cell content.

The Castelo-Branco research group is interested in the molecular mechanisms defining the epigenetic state of cells of the oligodendrocyte lineage. Our research group has performed single nuclei/cell RNA-Seq and identified several cell states within the oligodendrocyte lineage in development and disease (Science 2016, Dev Cell 2018, Nature Medicine 2018, Nature 2019). Our findings suggest that oligodendrocyte lineage cells might present other functional properties than previously thought.

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Your mission

The position is based at unit of Molecular Neurobiology (MBB), at Karolinska Institutet, Stockholm, Sweden, at the Ana Mendanha Falcão research group (also at University of Minho, Portugal) and joint with Castelo-Branco research group.

Falcao’s and Castelo-Branco's research groups have ongoing projects with single-cell and bulk transcriptomics, and the successful candidate will be actively working in specific projects under Falcao’s group together with Castelo-Branco’s group. The successful candidates will be integrated in a multidisciplinary team comprising computational, molecular and cellular biologists.

Your profile

We are looking for a highly motivated, driven, inquisitive and enthusiastic person interested in our area of research, and ready to explore new avenues in science. The candidates should have a collaborative approach to research, working productively in a team and contributing to a good social environment in the laboratory. The applicants must have either a Master in bioinformatics and computational biology or PhD degree, and strong programming skills (R and/or Python and/or others), UNIX and LINUX systems knowledge, familiarity with data science a big data. The successful candidate will be working in specific projects involving single-cell omics on the areas of interest Falcao’s group. Research experience and expertise in analysis of sequencing data is highly desirable. Wet lab experience is not required but it is an advantage.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Location: Solna (Stockholm, Sweden)


An employment application must contain the following documents in English:

  1. A complete curriculum vitae, including date of the Master or PhD defense, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work (nor more than 4 pages)
  2. A selected list of publications (no more than 2 pages)
  3. A personal letter highlighting previous scientific accomplishments, technical expertize and why the candidate is interested in joining the host lab (no more than one page)
  4. Verifications for crediting of illness, military service, work for labour unions or student organizations, parental leave or similar circumstances
  5. Verification from the thesis defense committee or the equivalent (only if the thesis defense is scheduled within three months after the application deadline)
  6. Two reference letters (to be uploaded in Varbi if already available, or to be sent directly to after the first selection round)

Welcome to apply at the latest 2020-07-03

The application is to be submitted through the Varbi recruitment system. 

All applicants will be informed when the recruitment is completed. 

Want to make a difference? Join us and contribute to better health for all

Type of employment Temporary position longer than 6 months
Contract type Full time
First day of employment October 2020
Salary Monthly salary
Number of positions 1
Working hours 100 %
City Stockholm
County Stockholms län
Country Sweden
Reference number STÖD 2-2504/2020
  • Ana Mendanha Falcão,
Union representative
  • Hongyan Xia, SACO,
  • Venus Azhary, OFR, 0707-124 127
Published 02.Jun.2020
Last application date 03.Jul.2020 11:59 PM CET

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