Do you want to contribute to top quality medical research?

The research at our Inflammation Physiology lab aims to understand the pathophysiological mechanisms of atherosclerosis, the underlying pathology for myocardial infarction and stroke and hence responsible for most deaths worldwide. We have identified the importance of neutrophils as key drivers of vascular inflammation, unveiled important processes these cells set off, and designed preclinical intervention strategies aimed at halting these processes (e.g. Silvestre-Roig, Nature, 2019; Paulin et al., Circulation, 2018; Alard et al., Sci Transl Med, 2015). In recent years we have learnt that acute cardiovascular events peak at a certain time of day and our studies have revealed circadian leukocyte recruitment as possible cause for such pattern (Winter et al., Cell Metab 2018). We have now teamed up with Novo Nordisk to map changes in circadian gene and protein expression in depth to develop innovative strategies of chronopharmacological intervention.

https://ki.se/en/fyfa/inflammation-physiology

Your mission & Your Profile

We are looking for a postdoctoral researcher who will employ advanced bioinformatics of transcriptomic and proteomic data sets to map changes across tissues over the day.

The applicant should have a PhD degree with focus on bioinformatics and have an interest in physiology, inflammation, and circadian biology. Basic understanding in systems biology and analysis of large scale data sets are required. Coding skills (e.g. R, python), the ability to set up pipelines, and the ability to work independently are needed. Taking own initiative to move this project forward is desired. Basic
understanding in simple wet lab techniques (e.g. RNA extraction) is a plus. Furthermore, good communication skills and good proficiency in spoken and written English are necessary.

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.


Location:
Biomedicum, Solna Campus 

Application

An employment application must contain the following documents in English:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

Welcome to apply

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Type of employment Temporary position longer than 6 months
Contract type Full time
Number of positions 1
Working hours 100%
City Solna
County Stockholms län
Country Sweden
Reference number 2-2142/2020
Contact
  • Oliver Söhnlein, PI, oliver.sohnlein@ki.se
Union representative
  • Henry Wölling, SEKO, henry.wolling@ki.se
  • Gunnel Brolin, OFR, gunnel.brolin@ki.se
  • Helin Norberg, SACO, helin.norberg@ki.se
Published 12.May.2020
Last application date 10.Jun.2020 11:59 PM CET

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