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The research at our Inflammation Physiology lab aims to understand the pathophysiological mechanisms of atherosclerosis, the underlying pathology for myocardial infarction and stroke and hence responsible for most deaths worldwide. We have identified the importance of neutrophils as key drivers of vascular inflammation, unveiled important processes these cells set off, and designed preclinical intervention strategies aimed at halting these processes (e.g. Silvestre-Roig, Nature, 2019; Paulin et al., Circulation, 2018; Alard et al., Sci Transl Med, 2015). In recent years we have learnt that acute cardiovascular events peak at a certain time of day and our studies have revealed circadian leukocyte recruitment as possible cause for such pattern (Winter et al., Cell Metab 2018). We have now teamed up with Novo Nordisk to map changes in circadian gene and protein expression in depth to develop innovative strategies of chronopharmacological intervention.
https://ki.se/en/fyfa/inflammation-physiology
We are looking for a postdoctoral researcher who will employ advanced bioinformatics of transcriptomic and proteomic data sets to map changes across tissues over the day.
The applicant should have a PhD degree with focus on bioinformatics and have an interest in physiology, inflammation, and circadian biology. Basic understanding in systems biology and analysis of large scale data sets are required. Coding skills (e.g. R, python), the ability to set up pipelines, and the ability to work independently are needed. Taking own initiative to move this project forward is desired. Basic
understanding in simple wet lab techniques (e.g. RNA extraction) is a plus. Furthermore, good communication skills and good proficiency in spoken and written English are necessary.
Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.
A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.
Location: Biomedicum, Solna Campus
An employment application must contain the following documents in English:
Welcome to apply
The application is to be submitted through the Varbi recruitment system.
Type of employment | Temporary position |
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Contract type | Full time |
First day of employment | Upon agreement |
Salary | Monthly salary |
Number of positions | 1 |
Full-time equivalent | 100% |
City | Solna |
County | Stockholms län |
Country | Sweden |
Reference number | 2-2142/2020 |
Contact |
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Union representative |
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Published | 12.May.2020 |
Last application date | 10.Jun.2020 11:59 PM CEST |