Do you want to contribute to improving human health?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

The Department of Clinical Science and Education, Södersjukhuset, pursues undergraduate education, research education and internationally recognized research focusing on common diseases and injuries. The goal of all activities is to improve human Health.

The NeuroCardioMetabol group is led by Associate Professor Cesare Patrone and Professor Thomas Nyström. Senior Researcher Vladimer Darsalia is responsible of the preclinical in vivo activities in animal models of stroke and diabetes. Our research focus is on the pathophysiological mechanisms at the basis of the complications of diabetes such as stroke, endothelial dysfunction, heart failure and dementia. The identification of new therapies, with special focus on the effects mediated by incretins is an important part of our research. Our research is translational as we employ clinically relevant preclinical experimental models in parallel to randomized clinical studies and epidemiological research.

The doctoral student project and the duties of the doctoral student

The mechanisms at the basis of why the recovery after stroke is diminished in people with type 2 diabetes (T2D) are largely unknown and need to be identified. The Ph.D. project aims to advance the knowledge in this field and will consist of performing stroke studies in rodent models of T2D in order to understand how T2D affects recovery after stroke as well as to identify efficacious therapies. The studies will consist in growing a colony of mice that will become diabetic under experimental conditions. We will then treat these mice with different pharmacological strategies before inducing stroke and follow their recovery by using behavioral test. Brains will be collected and analyzed with immunocytochemistry, biochemistry, molecular biology and statistical methods. The student will learn all these methods practically and also how to interpret the results.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement
You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

  1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree) or
  2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
  3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

- Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents
Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

Skills and personal qualities

We are looking for a highly motivated person who is committed to research. The candidate should have an interest in neuroscience and diabetes research.

Prior experience within neuroscience and/or diabetes research is considered an advantage for this project. Authorship on research articles is also highly meriting, as is previous training in research laboratories.

Methods used in the study include immunohistochemistry and biochemistry methods, as well as cellular and molecular techniques, and experience in these methods is desirable.

The following qualifications will be especially valued:

-Master’s degree in neuroscience

-Experience in immunohistochemistry techniques and Western blot analysis (basic molecular biology experience is desirable).

-Very Good knowledge in the English Language, written and spoken.

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.

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Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions.

Your application should contain the following documents:

- A personal letter and a curriculum vitae (Swedish or English)
- Degree projects and previous publications, if any (Swedish or English)
- Any other documentation showing the desirable skills and personal qualities described above (Swedish or English)
- Documents certifying your general eligibility (see A above)
- Documents certifying your specific eligibility (see B above)


A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

- Documented subject knowledge of relevance to the area of research
- Analytical skill
- Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

 All applicants will be informed when the recruitment is completed.

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Want to make a difference? Join us and contribute to better health for all

Type of employment PhD placement
Contract type Full time
Reference number 2-1124/2020
  • Cesare Patrone, +460704328349
Union representative
  • Gunnel Brolin, OFR, 08-524 810 63
  • Md. Shahidul Islam, SACO, 070-2593446,
Published 04.Mar.2020
Last application date 26.Mar.2020 11:59 PM CET

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