Do you want to contribute to top quality medical research?

Your mission

We are looking for a highly motivated co-worker with a PhD degree in an area relevant for this position. The project to be developed aims at characterizing novel interactors of the hypoxia-inducible factor 1-alpha (HIF-1a). The candidate will perform in vitro and in vivo assays to characterize the physiological function of newly discovered HIF-1a interactors. Generation of diverse plasmids and recombinant viral vectors will be used for expression and purification of recombinant proteins, biochemical and molecular experiments, both in vivo and in cell cultures, primary and immortalized. The candidate is expected to be heavily involved in project design, implementation, analysis, and interpretation, in close collaboration with other team members. The candidate is also expected to communicate scientific findings in conferences and articles published in peer-reviewed journals.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

The candidate should have experience in tissue culture techniques including the isolation, preparation, and maintenance of mouse primary myoblasts and hepatocytes. Additionally, the candidate should have experience with handling and manipulation of laboratory animals, and a strong background in animal physiology and molecular biology. The candidate should also be experienced in techniques necessary for the execution of the project, such as DNA cloning, protein expression and purification, quantitative real-time PCR, and generation and utilization of adeno and baculoviruses. Having FELASA A certification, experience with recombinant protein expression in insect cells and good knowledge of high-performance liquid chromatography are merits.

Excellent communication skills and an ability to interact socially and scientifically with other postdoctoral fellows and students in the laboratory and with collaborators in various networks are essential. A good command of the English language is needed for this position. The ideal candidate should be ambitious and strongly motivated to develop the proposed project, as well as hardworking, collaborative, efficient and innovative.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.


Location:
Biomedicum, Solna


https://ki.se/en/fyfa/department-of-physiology-and-pharmacology

https://ki.se/en/fyfa/the-ruas-lab-molecular-and-cellular-exercise-physiology

Application

An employment application must contain the following documents in English or Swedish:

  • A letter motivating the application for this position
  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

Welcome to apply at the latest 2019-11-17.

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Type of employment Visstidsanställning längre än 6 månader
Contract type Full time
Number of positions 1
Working hours 100%
City Solna
County Stockholms län
Country Sweden
Reference number 2-5456/2019
Contact
  • Jorge Ruas, jorge.ruas@ki.se
Union representative
  • Göran Engberg, SACO, 08-524 867 17
  • Niklas Andersson, OFR, niklas.andersson@ki.se
  • Henry Wölling, SEKO, 08-524 840 80
Published 04.Nov.2019
Last application date 17.Nov.2019 11:59 PM CET

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