The research conducted at the Research Division of Genome Biology (located at SciLifeLab and as part of the Department of Medical Biochemistry and Biophysics) explores various aspects of genome metabolism, and how their perturbation can lead to disease. Besides our basic research activities, we also focus on phenotypic screens aiming at finding genes or chemicals that can be of help in fighting against age-related diseases currently lacking a cure.

We are currently looking for an ambitious, highly motivated project leader with a solid background in cell, molecular biology, biochemistry and high-throughput screening, to join the research group of Prof. Oscar Fernandez-Capetillo.

For further information visit us at

Qualifications and requirements
The applicant should have a PhD in molecular biology or equivalent field and 4 years postdoc experience. Further, the successful candidate should have a solid background in cancer biology, with focus on genomic stability and cancer therapy.

The candidate must be proficient in standard techniques including:

  • Cell culture models such as mouse embryonic stem cells and cancer cells
  • Molecular biology, including western blotting, CRISPR/Cas9, cloning, transfection of shRNA and other vectors, RNA/DNA extraction, DNA fiber analysis, PCR and quantitative real-time PCR techniques
  • Cell viability, proliferation and apoptosis assays
  • Immunofluorescence staining and immunoprecipitation techniques
  • Fluorescence-activated cell sorting (FACS)

In addition, the candidate should have skills in various advanced microscopy methods including high-throughput imaging and live cell imaging. Experience of high-throughput techniques and imaging data analysis is required.

Preferable, the candidate has experience as project leader. As project leader, it is important to have the ability to organize, plan and document experimental bench-work at the highest level and the capacity to stay on top of the relevant research field.

Complete fluency in both written and spoken English is a request. The candidate’s communication and personal skills will be highly valued. The candidate will be expected to supervise Postdocs, PhDs and master students as well as to coordinate the research in the group. Writing grants and applying for funding will be requested, as well as designing and executing projects.

Application process
An employment application must contain the following documents in English or Swedish:
1. A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
2. A complete list of publications
3. A summary of current work (no more than one page)
The application is to be submitted through the Varbi recruitment system.

Karolinska Institutet is one of the world’s leading medical universities. Its vision is to significantly contribute to the improvement of human health. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine. Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published. Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone. For temp agencies and recruiters, and to salespersons: We politely, yet firmly, decline direct contact with temp agencies and recruiters, as well as those selling additional job announcements.

Type of employment Visstidsanställning längre än 6 månader
Contract type Full time
City Solna
County Stockholms län
Country Sweden
Reference number 2-4504/2019
  • Per Moberg, +46 8 524 81 266
Published 09.Sep.2019
Last application date 18.Sep.2019 11:59 PM CET

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