Karolinska Institutet, the Department of Medicine, Huddinge

We are recruiting a student for doctoral education. For more information regarding doctoral (PhD) education, see: http://www.ki.se/doctoral 

Research group
The Department of Medicine at Huddinge comprises seven units, three research centers and around 70 independent research groups. Integrated Cardio Metabolic Centre (ICMC) is a unique and innovative collaboration committed to advancing cardiovascular and metabolic disease research. The aim of the center is to advance the understanding of cardiovascular and metabolic disease within three main strategic areas: Cardiac Regeneration, Islet Health (Diabetes) and Diabetic Nephropathy.

The position available is in the laboratory of Professors Bo Angelin/Mats Rudling. The Department is located at Karolinska Institutet South Campus in Huddinge. The aim of the research group is to understand how lipoprotein metabolism is regulated in humans by endogenous (genetic) and exogenous (hormones, diet) mechanisms and how this may influence diseases such as cardiovascular, hepatic and metabolic diseases.

The position available is in the laboratory of Professors Bo Angelin/Mats Rudling. The Department is located at Karolinska Institutet South Campus in Huddinge. The aim of the research group is to understand how lipoprotein metabolism is regulated in humans by endogenous (genetic) and exogenous (hormones, diet) mechanisms and how this may influence diseases such as cardiovascular, hepatic and metabolic diseases.

The doctoral education project and the duties of the student
Diabetic dyslipidaemia involves both quantitative and qualitative circulating lipoprotein abnormalities that result in a shift towards a more atherogenic lipid profile. The interstitium represents the immediate surrounding environment of most cells in the body and its composition and functional properties should therefore be of high relevance in the pathogenesis of type 2 diabetes (T2D). The goal of this project is to further elucidate the link between peripheral lipoprotein metabolism occurring in both blood and interstitium and the potential mechanisms contributing to accelerated atherogenesis in T2D. The project will encompass studies of the functionality of lipoproteins, reverse cholesterol transport and peripheral cholesterol metabolism in both humans and animals. The PhD student will be involved in planning/designing and performing experiments; analyzing/interpreting the data and presenting the results at national and international meetings.

Eligibility requirements for doctoral education
In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

  1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree) or
  2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
  3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

  • Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

Skills and personal qualities
We are seeking a highly talented, driven and creative doctoral candidate with master degree in biomedicine, nutrition, biochemistry or corresponding field. Previous experience from working in a metabolic research lab is a merit as the project relies upon the candidate’s ability to work with cell cultures and perform immunoassays, including western blot, ELISA and 2-dimentional electrophoresis. Documented post-graduation experience within the field of lipid metabolism and the reverse cholesterol transport will be highly valued. The candidate must have good communication skills and be able to work both independently and as part of a team.

Assessment criteria
A selection will be made among qualified applicants on the basis of the ability to benefit from doctoral education. Karolinska Institutet uses the following bases of assessment:

- Documented subject knowledge of relevance to the area of research

- Analytical skill

- Other documented knowledge or experience that may be relevant to doctoral studies in the subject. The qualifications of the applicants will be evaluated on an overall basis.

Terms and conditions
All doctoral students at KI receive financial support during their doctoral education and employment on a doctoral studentship is the most common sort of support.The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.

Application process
Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions.

Your application should contain the following documents:

  • A personal letter and a curriculum vitae (Swedish or English)
  • Degree projects and previous publications, if any (Swedish or English)
  • Any other documentation showing the desirable skills and personal qualities described above (Swedish or English)
  • Documents certifying your general eligibility (see A above)
  • Documents certifying your specific eligibility (see B above)

All documents certifying the entry requirements must be scans of originals (scans of copies or certified copies will not be accepted). The scanned documents must be in color and both the front and the back of the documents must be scanned. Please note that there are specific documentation requirements for a number countries, please read the instructions at:

https://ki.se/en/phd/entry-requirements-eligibility-for-doctoral-education

The application and supporting documents are to be submitted through the Varbi recruitment system. All applicants will be informed when the recruitment is completed.

Type of employment Doktorandplats
Contract type Full time
Number of positions 1
Working hours 100%
City Huddinge
County Stockholms län
Country Sweden
Reference number 2-3621/2019
Contact
  • Mats Rudling, Mats.Rudling@ki.se
Union representative
  • Carina Eklund, Carina.Eklund@ki.se
  • Belinda Pannagel, Belinda.Pannagel@ki.se
Published 21.Jun.2019
Last application date 12.Jul.2019 11:59 PM CET

Tillbaka till lediga jobb