Karolinska Institutet, Institutionen för Medicinsk biokemi och biofysik, Molecular Structural Biology

Description of research group and project:
Possibly more than 50% of the human genome codes for non-coding RNA. These RNAs are ubiquitous among all life forms and the mechanisms how non-coding RNAs regulate these cellular functions are largely unknown.
Our research group is interested in understanding how RNAs adopt their structures in order to select specific functions in a pool if RNAs. We employ different biochemical and biophysical techniques (e.g. EMSA, NMR, UV melting experiments), to investigate the molecular mechanism of RNA function (Nature 2012 & 2015).

We look for a research assistant for an interdisciplinary project studying ribosomal RNA and the person will therefore be working on an interface from biochemistry to biophysical methods. The project aims to study structure & dynamics of ribosomal RNA and establish and develop biophysical and biochemistry methods for this task.
The a research assistant will work on RNAs addressing biological questions studied in the lab. You will work in a team together with other lab members and regularly present your research work in lab-meetings, seminars and at international conferences.
We are looking for a highly motivated, well organized, driven and enthusiastic person interested in our area of research, whom is ready to explore new avenues in science. The candidate should have a high degree of independence but should also show a collaborative approach to research and be able to work productively in a team.

The Department:
The Department of Medical Biochemistry and Biophysics conducts a broad spectrum of biomedical research and education within medical biochemistry and biophysics. Presently our department consists of 12 research divisions with a total of approximately 450 employees.
We are looking for a highly motivated a research assistant that will work in Katja Petzold’s group at the Department of Medical Biochemistry and Biophysics.

Entry requirements for a research assistant position at KI
General entry requirements:

  1. has been awarded advanced/second-cycle/master qualification (i.e. master degree) or

  2. has satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the second-cycle/master level, or

  3. has acquired substantially equivalent knowledge in some other way in Sweden or abroad.

Specific entry requirements
: Proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school: Proficiency in the English language can be documented by an internationally recognized test such as TOEFL or IELTS, see web-link below for more information.
Applicants who meet the general entry requirements (1 or 2 above) from a university in one of the Nordic countries fulfill the requirements in English.

Assessment criteria
A selection will be made among qualified applicants on the basis the following parameters:

- Documented subject knowledge of relevance to the area of research
: Experience with laboratory work in RNA biochemistry for structural sample preparation and previous work with Nuclear Magnetic Resonance (NMR), python programming and RNA structural biology are of great advantage.

- Analytical skill

- Other documented knowledge or experience that may be relevant to the subject

The qualifications of the applicants will be evaluated on an overall basis.

Terms and conditions
A short-term employment will as a research assistant be offered for up to 6 months.

Application process
An application must contain the following documents in Swedish or English:

  • A personal letter (max. ½ page) and curriculum vitae (containing a list of relevant courses, work experiences, skills & competencies)
  • A copy of degree certificates and associated certificates
  • A copy of degree projects and any previous publications

At Karolinska Institutet a 6-month trial period is required for all permanent appointments.

Type of employment Temporary position longer than 6 months
Contract type Full time
First day of employment upon agreement
Salary Monthly
Working hours 100 %
City Solna
County Stockholms län
Country Sweden
Reference number 2-2952/2019
  • Katja Petzold, +46 8-524 876 47
Union representative
  • Anne Edgren, OFR/S, P, O, 08-524 87570
  • Henry Wölling, SEKO, 08-524 840 80
Published 15.May.2019
Last application date 25.May.2019 11:59 PM CET

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