Karolinska Institutet, Department of Biosciences and Nutrition, BEA (FFA)

The Department of Biosciences and Nutrition performs research and education in several areas of medical science including bioorganic chemistry, molecular endocrinology, cancer biology, functional genomics, systems biology, epigenetics, structural biochemistry, cellular virology, and nutrition. It offers an excellent international research and working environment, including around 300 scientists, students, administrative and technical personnel. The Department resides in the new biomedical research building Neo, aimed at being a creative and open environment that enables meetings, synergies, and exploration of areas of mutual interest across disciplines.

Division
BEA, the core facility for bioinformatics and expression analysis, Department of Biosciences and Nutrition, Karolinska Institutet is looking for a full time research engineer. The BEA laboratory is located in the NEO building at the Karolinska South Campus in Huddinge. Today the group includes four research engineers and two bioinformaticians.

BEA - www.bea.ki.se - is a national genomic service facility that provides an extensive repertoire of genomic technologies to ongoing research projects principally at the Karolinska Institutet but also at other Swedish universities. The services include genomic analysis mainly based on the Affymetrix, Agilent, Illumina and ABI platforms for microarrays, next generation sequencing (NGS) and qPCR. Using the platforms above the core facility is responsible for performing high throughput assays including gene expression profiling, genotyping, methylation analysis, chromatin immunoprecipitation and sequencing. The services are very broad and ranges from experimental planning to bioinformatic support.

Duties
The successful candidate will be responsible for various sequencing and microarray based expression and genotyping analyses. This includes all steps from assisting in experimental design, DNA/RNA purification, sample preparation and labeling, sequencing library preparation, gene expression/ genotyping analysis by microarray and NGS including data analysis. The position will also include method development and validation, responsibility for quality management and coordination of the quality work. A limited amount of education is also part of the responsibility to spread knowledge about services available through the core facility.

Qualifications
The successful applicant must have:

  1. Degree in molecular biology or equivalent.
  2. Experience of working with DNA and/or RNA based high throughput functional genomics technologies is required.
  3. Experience in working with DNA and/or RNA extraction methods.
  4. Experience in working with the Affymetrix and Illumina platforms.
  5. The applicant must have experience with working at a core facility or equivalent.
  6. Knowledge in robotic liquid handling and general good computer skills.
  7. Experience of quality management in a laboratory environment. In general the applicant must have very good computer skills and knowledge of statistical analyses.
  8. Experience with basic bioinformatics procedures and processing of high throughput sequencing data in a Linux and Java based environment.
  9. The work is performed in close collaboration within the unit and with our customers. Good communication skills in both Swedish and English are thus necessary.
  10. The successful candidate should show an interest in employing new technologies, be used to pursue lab work requiring high precision and be used to working in a dynamic environment with deadlines to meet.

 We put great emphasis on personal suitability.

Application process
The application is to be submitted on the MyNetwork recruitment system.

The application should be in pdf format and contain a maximum of four A4 pages in total and must contain the following documents;

- One page cover letter.

- One to two page CV.

References or a letter of recommendation will be requested at a later stage.

At Karolinska Institutet a 6-month trial period is required for all permanent appointments.

Type of employment Tillsvidareanställning
Contract type Full time
City Huddinge
County Stockholms län
Country Sweden
Reference number 2-6563/2018
Contact
  • Fredrik Fagerström Billai, +46-8-524 835 43
  • Thomas Tinglöv, Head of Administration, +46-8-524 835 49
Union representative
  • Henry Wölling, SEKO, +46-8-524 840 80
  • Birgitta Lindqvist, OFR, +46-8-524 810 28
Published 29.Nov.2018
Last application date 20.Dec.2018 11:59 PM CET

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