Research Assistant Position

Do you want to contribute to top quality medical research?

Join the Division of Molecular Neurobiology at the Department of Medical Biochemistry and Biophysics, Campus Solna. The research group led by Professor Gonçalo Castelo-Branco investigates the molecular mechanisms shaping the transcriptomic and epigenomic states of oligodendrocyte lineage cells in neuroinflammatory and demyelinating conditions such as multiple sclerosis. We employ cutting-edge approaches, including single-cell and spatial transcriptomics/epigenomics and CRISPR-based screens using both rodent disease models and human patient material.

As our multidisciplinary team continues to grow, we are now seeking a motivated individual to support a variety of tasks within our ongoing research projects.

Your mission

Assist and perform various laboratory experiments, such as

• Molecular biology and cloning techniques, such as plasmid preparation (bacterial transformation, mini–maxi preps), CRISPR/Cas9 genome-editing and cloning of plasmid vectors, including PiggyBac-based systems.
• Lentiviral vector production.
• In vivo experimental procedures, including colony maintenance, rodent handling, perfusion, administrations via diverse routes, animal journal keeping, monitoring and reporting animal’s health status to the supervising researcher
• Perform duties such as placing orders, maintaining laboratory premises, equipment and consumables stock

Your profile

• Relevant education in biomedical sciences, molecular biology, or biotechnology.
• Required to have documented experience in experimental procedures in rodents, including holding a FELASA certificate or equivalent
• Proficient in both spoken and written English.
• Highly motivated to keep updated about animal welfare legislation
• Good teamwork skills and ability to work autonomously
• Ability to work calmly and methodically under time constraints
• Meritorious to have experience from surgical procedures in rodents and animal disease models

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is also a state university, which entitles you to several good benefits through our collective agreement. And you get to practice freely in our modern wellness facilities, where trained staff are on site.

Location: Solna

Application

The application is to be submitted through the Varbi recruitment system. In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form. 

Want to make a difference? Join us and contribute to better health for all