Postdoctoral Researcher in cardiovascular medicine and stem cell biology

Do you want to contribute to improving human health?

A postdoc position is available in the research group of Professor Kenneth Chien. The central scientific interest of his group is to understand heart development at the molecular and cellular level, with the ultimate goal of applying the developmental principles, logic, pathways, technology, and model systems to unravel human heart disease.

Your profile

We are seeking for a highly motivated and enthusiastic postdoctoral researcher to elucidate cardiogenesis in cell culture systems and animal models. The candidate is expected to work with animal models and embryonic stem cells, manipulate embryos, perform molecular cell biology and imaging techniques, perform bioinformatics analysis, and create relevant software applications. The candidate is expected to be able to work independently with the projects.

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

Entry requirements

The successful candidate must have strong background in cardiogenesis, developmental biology and bioinformatics. The candidate is expected to have extensive training with mouse models and systems, as well as holding FELASA B and C certificates or equivalent. The candidate should have a strong publication record in top-ranking journals. The candidate must be fluent in English (both spoken and written), and demonstrate excellent communication skills, documented by participation in international meetings. The candidate’s personal skills will be highly valued.

Specific skills required

Strong background in cardiac development, molecular biology and cell signaling
Experience in working with different mouse models, including disease models and cell lineage tracing models.
Experience in cell line culture under normal conditions and in hypoxic conditions
Experience with immunohistochemistry and confocal microscopy
Experience in bulk and single cell RNA-seq analysis
Experience in R, C# and Python programming languages
Documented experience of gene manipulation methods, CRISPR/Cas9 technology

Meriting skills

Experience in manipulation of mouse embryos and mouse hearts
Experience in working with hypoxic chamber
Experience in web application or software development

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Location: Solna

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
A complete list of publications
A summary of current work (no more than one page)
A letter of recommendation (1)

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all