Postdoctoral Researcher in translational tumor pathology

Do you want to contribute to top quality medical research?

The Department of Laboratory Medicine consists of seven divisions and is active in many areas of Laboratory Medicine. The department is involved in advanced basic scientific, clinical, and epidemiological research. The department is one of the largest departments of education at Karolinska Institutet.

Your mission

Mikael Björnstedt’s research group is searching a postdoctoral researcher to study the antitumor effects of selenium compounds as cancer therapeutics, we perform translational and clinical studies focusing on redox-active selenium compounds as chemotherapeutic treatment of cancer. The research has a wide span including both clinical trials and mechanistic studies with focus on drug action.

Primary duties included in the role are:

• Managing your own research projects
• Teaching and supervision of junior staff, students
• Ongoing contact with collaboration partners
• Writing and publishing of scientific articles

Your profile

A qualified candidate for the postdoctoral position is one who has obtained a doctorate or possesses equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director, or equivalent.

We are seeking a PhD with a background in biomedical engineering, pathology, and cancer therapy. The successful candidate will join an interdisciplinary research group closely collaborating with clinical departments and other national and international research groups. Therefore, experience in a similar field is advantageous during the selection process.

In addition to the mentioned qualifications, we encourage candidates with a keen interest in basic biostatistics and RNA sequencing to apply. A strong background in molecular biology techniques is essential, including expertise in miRNA detection by qPCR and in situ hybridization, protein detection by Western blot, as well as proficiency in molecular pathology methods (frozen and fixed samples preparation and handling from fresh patient-derived tissues, immunohistochemical and immunofluorescent labeling, FISH, RNAscope).

The candidate should also demonstrate expertise in wet lab molecular biology methods such as in vitro culturing and ex vivo patient-derived organotypic culturing. Experience with selenium compounds, previous research on cell death, investigation of the effect of chemotherapy agents on different molecular pathways, and familiarity with gastrointestinal tumors such as pancreatic, liver, biliary, and colon tumors are necessary qualifications for the applicant.

While previous experience in postdoctoral studies at KI is an advantage, it is not a mandatory requirement. As an individual, we are looking for someone who is creative and motivated with strong collaboration skills. We consider personal qualities important, and excellent proficiency in both written and verbal English is a prerequisite for the role.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Flemingsberg

Read about Mikael Björnstedts research group. 

Read about the Department of Laboratory Medicine

Application

An employment application must contain the following documents in English or Swedish:

• PhD certificate
• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

Welcome to apply!

The application is to be submitted through the Varbi recruitment system.

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