Postdoctoral Researcher in virus and vaccine immunology with specific focus on T cells

Do you want to contribute to top quality medical research?

A position is now open in Professor Malin Flodström Tullberg’s group to study immune responses to infections and vaccines targeting viruses associated with the development of type 1 diabetes. The research group focuses on the natural history of type 1 diabetes and the development of preventative treatments. The successful candidate will join a stimulating research environment at the Department of Medicine, Huddinge, Karolinska Institutet and be part of a new international EU consortium.

Your mission

The main focus of the studies is to monitor T cell responses induced by infection and vaccination. The studies build on recent work identifying epitopes recognized by CD8+ T cells during infections by viruses linked to type 1 diabetes and include the use of humanized mouse models, enteroviruses and new vaccines against such viruses. Assessments include the use of methods to monitor virus replication and tissue damage, HLA-I multimer assays and advanced flow cytometry. The studies may also include investigations into the B cell- and antibody response to infection and vaccination.

The candidate is expected to contribute to experimental design, experimentation, data analyses and publication of results. Furthermore, the candidate will participate in various research-related activities including group meetings, departmental seminars, national/international scientific meetings, as well as contribute to routine work within the research group and help supervise students within the group.

The work will be carried out at the Center for Infections Medicine (CIM), Karolinska Institutet and in collaboration with a group led by Professor Roberto Mallone, at Insitute Cochine, Paris. The position is funded via a Horizon Europe grant (ENT1DEP) and the candidate will have the opportunity to interact with and learn from leading researchers in the diabetes immunology field.

Your profile

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

We are looking for a highly motivated postdoctoral researcher with a strong interest in studying immune responses to viruses and vaccines. Applicants must have a PhD degree in immunology, virology, vaccinology or a related discipline. Previous experience with experimental murine models and FELASA-A is a requirement. The candidate must also have experience in isolation of immune cells, cell culturing and master multidimensional flow cytometry analysis. Knowledge of virology, immunology and/or vaccinology and experience in molecular biology techniques, and bioinformatical analyses are meritorious. Excellent language skills in English, both spoken and in written, are a requirement. The applicant must be structured, thorough, independent, flexible, able to work with several different tasks simultaneously and work productively in a team.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Flemingsberg

Choose to work at KI – Ten reasons why

Read more about the department and the research group here:

Center for Infectious Medicine (CIM)

Malin Flodström-Tullberg group

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
A complete list of publications
A summary of current work (no more than one page)

Welcome to apply at the latest 2024-02-04

The application is to be submitted through the Varbi recruitment system.

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