Research specialist in epigenetic and transcriptional regulation of hematopoiesis and acute myeloid leukemia (AML). - Hiring in process/Finished, not possible to apply

Do you want to contribute to top quality medical research?

We are looking for a Research Specialist to Andreas Lennartsson´ s research group at the department of Biosciences and Nutrition (https://ki.se/en/bionut/department-of-biosciences-and-nutrition)

Description of the subject area

The epigenetic machinery is often perturbed in AML and contributes to leukomogenesis via different mechanisms. Increased knowledge about the aberrant epigenetic machinery will help us to better understand the mechanisms that give rise to AML. Andreas Lennartsson’s research group is interested in the epigenetic regulation of normal myelopoiesis and acute myeloid leukemia (AML),  https://ki.se/en/bionut/epigenetic-regulation-of-leukemia-and-normal-blood-development-andreas-lennartsson. The aim is to identify key epigenetic factors that regulate enhancer activity and multi-potency in hematopoietic stem cells and dissect how they contribute to the development of leukemic stem cells. 

Your mission

The employed Research Specialist is expected to perform research and provide academic leadership in experimental and translational molecular AML  biology, with a particular emphasis on transcrptomics and epigenomics, both experimental and bioinformatic work.. You will develop the field through internal and external collaborations, supervise master students and lead the day-to-day work of participating PhD students and postdocs; prepare and submit grant applications.

The position is time-limited for 6 months.

Eligibility requirements

To be eligible for employment as a Research Specialist, in addition to holding a Degree of Doctor, PhD, or having equivalent scientific expertise, the applicant must have demonstrated research expertise as well as have documented research experience after defending their doctoral dissertation. The applicant should hold a PhD from a related area, with experience in bioinformatic analysis of genome-wide data of especially Transcient Transcriptomics sequencing, CAGE, ChIP-sequencing, RNA-seq and the Illumia arrays for DNA methylation. Prior experience in Acute myeloid leukemia and IPS-cells are advantageous. Candidates should be able to interact and work efficiently in a team and experience in interaction with clinics. Good knowledge of both spoken and written English is required.

Emphasis will be placed on personal suitability.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Here, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Flemingsberg Campus

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Application

We prefer that Your application is written in English, but You can also apply in Swedish. An application must contain the following documents: 
- A letter of motivation 
- Curriculum vitae
- A complete list of publications 

Welcome to apply at the latest 13 August 2023.

The application must be submitted through the Varbi recruitment system.

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