Postdoctoral researcher in dementia treatment focus on the cholinergic system - Hiring in process/Finished, not possible to apply

Do you want to contribute to top quality medical research?

Research group and project

The postdoctoral researcher will join a multidisciplinary research team of doctors, statisticians, engineers, and basic researcher working to detect factors to prevent dementia, slow cognitive decline in patients with dementia and ensure high quality and equal access to dementia care throughout Sweden.  

The Eriksdotter research group conducts registry research using the Swedish Registry for Cognitive and Dementia Disease, SveDem, (with over 110 000 patients) and other registries merged to SveDem. For this project SveDem is merged with other registries to add information on all hospitalizations and diagnoses from outpatient specialist clinics, all prescribed medications, socioeconomics, long-term care for older individuals, kidney function and other laboratory biomarkers and death and its causes. Our datasets also include cerebrospinal fluid biomarkers and neuroimaging data. We aim to determine which treatment pattern (adherence, compliance, and combination) targeting the cholinergic system modify disease progression including cognitive decline, functional and mortality outcomes in different dementia types. To this end we will use cognitive follow-ups from SveDem measured with the Mini-Mental State Examination (>144 000 measures), functional outcomes such as nursing home placement or homecare, and mortality. The candidate will have the opportunity to develop their own projects with this data. 

Your mission

We are looking for a candidate with a strong background in statistics both classic and advanced statistical methods.

Your duties will include independent management of large datasets, from data cleaning, data extraction, research protocol development, performing statistical analysis at an advanced level, article writing and driving research results through all stages of peer review until successful publication. Divulging results through participation in scientific congresses is also expected. Additionally, the postdoc is expected to collaborate and communicate with other members of the Eriksdotter research group, provide statistical support for different projects in our group and receive training in clinical aspects and the SveDem cohort.

Developing your own research projects and collaborations within the field of the cholinergic system is encouraged. A successful candidate can explain complex information to team members with different knowledge and/or academic backgrounds

Your profile

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

We are looking for a candidate with a strong background in statistics, experience in statistical methods to adjust for confounding for indication in pharmaco-epidemiological studies, and experience in prediction modelling are desirable. The candidate should have a PhD in statistics, biostatistics, pharmacology, pharmacy, medicine, computer science, health data sciences, or other relevant discipline.

Demonstrable advanced skills and expertise in R, Python, SAS, STATA programming, or similar languages are required. Knowledge of Swedish healthcare organization is desirable.

What do we offer?

This position is a fixed-term contract for two years 

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Flemingsberg 

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Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

Welcome to apply at the latest 31th of may 2023

The application is to be submitted through the Varbi recruitment system.

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