Postdoctoral Researcher in regenerative bioinformatics

Do you want to contribute to top quality medical research?

We are at present a research group of six people at the Department of Neurobiology, Care sciences and Society, Division of Neurogeriatrics. We have a long-standing interest in spinal cord injury and repair, with a particular focus on human stem cell therapy. As a consequence we also have research projects that are of more developmental nature, and those that address applied stem cell biology. We are one of the partners in the Human Developmental (https://hdca-sweden.scilifelab.se) – a part of the international Human Cell Atlas initiative (humancellatlas.org) – and collaborate closely with research groups in other departments at Karolinska Institutet, as well as groups at SciLifeLab / Royal Institute of Technology (KTH) and Stockholm University

Your mission

We have a position as post-doc open in our research group to study regeneration and repair after spinal cord injury. Our long-term goal is to improve residual functions by transplanting neural stem and progenitor cells, and/or enhance repair by endogenous stem cells. To achieve this, we need to better understand the development of human stem/progenitor cells, mechanisms of fate specification and differentiation in vitro and in vivo, and the genetic regulation of these processes as well as the role of the local environment. We apply a multi-omics strategy, and combine it with immunofluorescence, FACS and cell transplantation experiments.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence within Genetics, Systems Biology, Computational Biology, Neuroscience or a related field. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

You should be familiar with sequencing data, especially from single-cell RNA sequencing, ATACseq, and spatial transcriptomics datasets, including data integration. You should be able to develop computational methods to solve specific questions during data analysis. It is advantageous to have experience in cell culture techniques, flow cytometry/FACS or CNS injury research. You should have good communication skills in English as well as collaborative skills to allow you to work closely with other post-docs and researchers with expertise in the techniques we apply

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden.

We recognize and support the need for you as a post-doc to improve your skills and broaden your competence to further your future career, whether it will be in academia or in corporate business. We are also aware of how important it is for post-docs to get published in high quality scientific journals.

Post-docs at KI can access the support by KI Career Service, and the KI Postdoc Association (KIPA) is a community available for all post-docs. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Department of Neurobiology, Care Sciences and Society

The Department of Neurobiology, Care Sciences and Society (NVS) conducts world leading research in aging, dementia, neurodegeneration, epidemiology and care sciences. This research extends from basic molecular and cell levels to clinical research and societal studies. NVS educates almost a third of KI students at basic and advanced levels. The Department has approximately 520 employees and a revenue 2021 of 483 million SEK. It comprises seven divisions, located at Campus Flemingsberg and Campus Solna.

The research group is part of the Division of Neurogeriatrics which comprises around 65 people, mainly located in the new BioClinicum building, Solna. The research focus of the Division is neurodegenerative diseases and disorders, and Alzheimer’s disease, Parkinson’s disease, stroke and CNS trauma are addressed by research groups in our divisio

Location: Solna

Choose to work at KI – Ten reasons why

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work.

A complete list of publications.

A summary of current work (no more than one page).

Welcome to apply at the latest 23rd of october

The application is to be submitted through the Varbi recruitment system.

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