Postdoctoral position in SARS-CoV-2 immunology

Do you want to contribute to improving human health?

We are looking for an ambitious postdoctoral fellow with solid immunology and gene-editing skills to join our highly accomplished team. We offer a stimulating environment in a rapidly moving research frontier. The successful candidate will be part of a cluster of other researchers working on similar topics.

Your mission

The Buggert group conducts innovative studies of cell-mediated immunity in health, cancer and viral disease. These studies are translational in nature and involve the usage of cutting-edge bulk- and single-cell technologies including high-parameter flow cytometry, gene-editing, RNA-seq, ATAC-seq, TCR-seq and proteomics analysis to dissect the heterogeneity and function of memory T cell immunity. Through these platforms, we study different aspects of human memory T cell biology, with an overall aim to i) study the heterogeneity of circulating and resident memory T cells in human organ donors, ii) identify alternative functions of memory T cells in human tissues, and iii) understand how memory T cells maintain control of tumors and viral infections, such as SARS-CoV-2.

The postdoctoral candidate will work with questions centered on SARS-CoV-2-specific T cell immunity after vaccination and infection. The candidate will also work in close collaboration with different members of the group to support and educate other peers in the implementation of gene-editing technologies (e.g. CRISPR-Cas9) to mechanistically dissect different functions of human memory T cell biology in viral disease. As such, we are seeking a postdoctoral candidate with a PhD, who will work as an integrated member in our team, being involved in several ongoing projects and drive his/her own project forward.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

To be eligible for employment as a postdoctoral candidate, in addition to holding a PhD in the field of biomedicine, must have demonstrated research expertise as well as have documented research experience in the field of human T cell immunology after defending their doctoral dissertation.

The candidate should have been trained in biotechnology and immunology during her/his PhD studies. The candidate should fully master (requirement) gene-editing technologies, such as CRISPR-Cas9, siRNA etc. In addition, a strong candidate should have a strong background in studies of human T cell biology in viral infections, including SARS-CoV-2. Experience of sequencing techniques, flow cytometry, and virus-specific T cells will also be considered as merits. Applicants should have first author publications in recognized peer-reviewed journals. Fluency in English is a requirement.

It is particularly meritorious that the applicant has

Been trained in Immunology during her/his PhD studies
Publications in the field of human T cell immunology
Fully master gene-editing technologies (e.g. CRISPR-Cas9)
Statistical knowledge
Worked with multiparametric flow cytometry data sets
Extensive cell culture background
Adaptive immunology background
Fluency in English

It is meritorious that the applicant has

Laboratory molecular and cell biology skill sets (e.g. preparation of RNAseq libraries)
Been trained in biotechnology during her/his Bachelor or Master studies

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Flemingsberg

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
A complete list of publications
A summary of current work (no more than one page)

Welcome to apply at the latest 2022-06-28.

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all