Postdoctoral Researcher in in epigenetics of neuroinflammation - Hiring in process/Finished, not possible to apply

Do you want to contribute to top quality medical research?

The Department of Clinical Neuroscience conducts research and education in the field of neuroscience from the molecular level to the society level. The successful candidate will work in Assoc. Prof. Maja Jagodic’s group, physically located at the Center for Molecular Medicine. The group studies epigenetic mechanisms underlying neuroinflammation and neuronal loss in Multiple Sclerosis (MS) using both largescale omics approaches and molecular in vivo and in vitro functional experiments.

Your mission

MS is an immune-mediated disease triggered by complex interactions between genetic and environmental factors resulting in a highly heterogeneous disease with respect to its clinical presentation and treatment response. We are looking for a postdoctoral researcher who will develop and implement bioinformatic pipelines to analyze epigenetic screens and to stratify patients based on omics data. The work will include design of analysis, data processing, quality control, statistical analysis, data interpretation and presentation of findings in the form of scientific publications, grant applications and at meetings and conferences. The candidate is expected to interact with many collaborators at KI and externally and to contribute to the efficient functioning of the unit.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

We are looking for a postdoctoral researcher who shares our passion for translational epigenetics, is ready to join our very collaborative team, and is highly motivated to perform computational work. The position is funded through the European Research Council (ERC-CoG) grant - Epi4MS.

Absolute Requirements

• PhD which must include research related to bioinformatics in life sciences
• Documented clinical and biological knowledge of neuroinflammatory and neurodegenerative diseases, in particular Multiple Sclerosis
• Demonstrated skills in multi-omics data analysis and interpretation
• Documented expertise in network analysis and complex disease research
• Excellent programming proficiency especially in R, Python, and bash
• Practical experience with linux based high-performance computing
• Knowledge of current machine learning methods (e.g. Random Forest) and frameworks (e. g. PyTorch, TensorFlow, Keras)
• Able to work with code repositories, version control (git) and understanding of code reproducibility
• Good knowledge of genetics, epigenetics and biostatistics
• Good knowledge of spoken and written English

Preferred Requirements

The candidates should also have good interpersonal skills and the ability to work both independently but also as a part of a large team. In addition, good communication skills are desirable and documented ability to collaborate. Experience with writing scientific papers and grant applications is a merit.

What do we offer?

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.

Location: Solna

Read more about the Department of Clinical Neuroscience  

Read more about the research group you will be part of

Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

Welcome to apply at the latest 18th December 2020.

The application is to be submitted through the Varbi recruitment system.

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