Principal Researcher to Karolinska Institutet - Hiring in process/Finished, not possible to apply

Do you want to contribute to improving human health?

The Department of Oncology-Pathology conducts basic, translational, and clinical research together with educational activities related to cancer. The department consists of more than 30 research groups localized at the Bioclinicum facility, Science for Life Laboratory (SciLifeLab) and Karolinska University Hospital, Solna. These groups represent know-how in innovative technologies as well as in pre-clinical and clinical research with the joint ambition to make a difference for the lives of cancer patients.

Description of the subject area

We are seeking a highly motivated applicants whose activities relate to basic cancer research on clinically relevant issues and have a clear focus on patient benefit. We are interested in candidates pursuing research centered upon gaining a better understanding of commonly used cancer therapies, in particular conventional antimetabolite therapies of importance in acute leukemias, their modes-of-action and resistance mechanisms, and leveraging this information to propose strategies to refine their clinical use. We welcome candidates employing multi-disciplinary approaches, such as combining biochemical and biophysical methods to understand enzyme structure-function, together with cell biology to define underpinning molecular mechanisms of biological phenomena through both hypothesis-driven and hypothesis-free approaches. Previous experience and documented expertise in the research areas of genome stability and nucleotide metabolism, and the relation of these to cancer biology and chemotherapy mechanism-of-action, is key.

Your mission

Applicants will act as principal investigators and conduct high-quality research in the subject area, supervise doctoral students and doctoral junior researchers (post-docs) and develop the field through collaborations with other colleagues in experimental and clinical activities locally, nationally and internationally. In addition to being a supervisor for doctoral students, the successful applicant is expected to contribute to the teaching of undergraduate and postgraduate students in the subject. It is of great importance that the applicant can work together with other researchers in collaborative efforts.

Eligibility requirements

To be eligible for employment as a Principal Researcher, in addition to holding a Degree of Doctor, PhD, or having equivalent scientific expertise, the applicant must have demonstrated research expertise. The applicant must also be a Research Leader and have established their own line of research. The applicant should furthermore have shown documented, high-quality scientific production, particularly in the last six years and have the potential to energetically drive their research forward as well as be recognized nationally and internationally. The applicant should also have obtained good, long-term and preferably external funding and have the potential to obtain further external funding.  The applicant should have shown teaching and supervision experience and demonstrated good leadership qualities.

Assessment criteria

It is particularly meritorious that the applicant has shown

• An independent line of research.
• Documented expertise related to all of the subject areas listed above.
• Publication of several original scientific articles corresponding author.
• Supervision of BSc, MSc, and PhD students, as well as postdocs and visiting scientists.
• Organisation of PhD-level courses related to subject areas
• Ability to obtain own competitive research funding and availability of external funding, such as personal or project grants from national agencies (e.g., VR, Cancerfonden, Barncancerfonden).

It is meritorious that the applicant has shown

• Documented leadership training

After an overall assessment of the expertise and merits of the applicants in relation to the subject area, Karolinska Institutet will determine which of them has the best potential to contribute to a positive development of the activities at KI.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Here, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several 

Location: Solna

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Application

We prefer that Your application is written in English, but You can also apply in Swedish. An application must contain the following documents: Resumé, qualifications and description of planned research, presented in accordance with Karolinska Institutet's qualifications portfolio.

Welcome to apply at the latest 18^th September. 

The applications will be reviewed by external reviewers.

The application must be submitted through the Varbi recruitment system.

Permanent position is initiated by a six months trial period.

Want to make a difference? Join us and contribute to better health for all