Postdoctoral studies, employing Bioinformatic gene-expression analysis in Neurobiology (scholarship)

Do you want to contribute to top quality medical research? 

Are you an enthusiastic and ambitious researcher with an interest in neurobiology and bioinformatics? We are searching for a postdoctoral fellow to conduct groundbreaking gene expression analyses in neurodegenerative diseases. Take the opportunity to work in an international environment with world-leading research and contribute to the development of new diagnostic biomarkers and treatment strategies for Alzheimer's disease.

Division

The division of Clinical Geriatrics consists of a multi-disciplinary team of 50 employees, at the forefront of translational Alzheimer's disease (AD) research using cutting-edge technology with aims to develop new diagnostic biomarkers and new treatment strategies in AD. We work in an inter-disciplinary environment which provides ample opportunities to enhance our understanding and skills.

Duties

Our group specializes in therapeutic applications targeting cholinergic pathways, primarily using Nerve Growth Factor (NGF) via encapsulated cell (EC Biodelivery) or cholinesterase inhibitors (ChEI’s) towards Alzheimer’s disease (AD) therapy. We aim to further our work by performing in-depth gene expression analysis from high-throughput sequencing projects, employing in-vitro, preclinical and clinical studies.

This position involves designing and executing experiments, data management and analysis, manuscript preparation, presenting research, contributing to grant proposals and mentoring students. The candidate will analyze and integrate next-generation sequencing data and have the opportunity to publish in high-profile papers, with national and international collaborations.

The ideal candidates should hold a PhD in Bioinformatics, Computational Biology or a related field, with experience in omics data analysis (e.g., single-cell RNA-seq, bulk RNA-seq, ChIP-seq, methylation data, or any other). Proficiency in analyzing single-cell ATAC-seq and spatial transcriptomics, programming languages and advanced bioinformatic tools is an asset. The candidate should have an interest in neurodegenerative diseases and a proven record of high-quality scientific research and publications. Excellent verbal and written English skills and the ability to write and apply for grants are required.

We are looking for a self-motivated scientist who can coordinate collaborative projects.

Entry requirements

Postdoctoral scholarships may be established for foreign researchers who pursue their postdoctoral research in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.

A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.

To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Here, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Students and employees have free access to our modern gym facilities with trained staff on site.

Location: NEO-building, Karolinska Institutet, Huddinge campus syd, Sweden

Type of scholarship

This is a postdoctoral scholarship for one year, with the possibility of a second year. The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system.

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