Do you want to contribute to the development of new immunotherapies for cancer?

In our lab we focus on the tumor microenvironment to find targets for immunotherapy for cancer. We have found that targeting using specific antibodies for Tumor Associated Macrophages (TAM) can be used for treatment of cancer (PNAS; 2020, 15;117 and Cell Rep; 2016, 100;2000). We are now developing this treatment for human application and are also investigating other possibilities for modifying the functions of TAMs for treatment purposes.

Division

Prof. Mikael Karlssons group is at the Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet, in Solna (Biomedicum). The department conducts research and teaching in immunology, infectious biology, cell biology and cancer. Our keywords are interdisciplinary, clinically based basic research and national and international cooperation.

Duties

The postdoc will work to understand the interplay between TAMs and other immune cells in the tumor as well as investigate the metastatic niche in lympnodes. The lab use animal models of cancer as well as in vitro systems including live imaging. We also investigate patient material, molecular and biochemical methods as well as omics approaches. Most of the methods to be used for the projects has already been setup and this project has support form and NIH grant and is done in collaboration with Rockefeller University in New York. The project can be modified to fit to the interest of the candidate and will involve both in vivo an in vitro work.

Qualifications of the applicant

  • Candidates should have a strong background in tumor biology and/or tumor immunology and demonstrate a promising publication record with at least one first-author peer-reviewed publication.
  • Proficiency in multi-parameter flow cytometry and mouse cancer models is a requirement.
  • Skills in bioinformatics and cell culture experience is an advantage.
  • The candidate should be self-motivated, have good communication skills and ability to interact effectively and work productively in a team. Emphasis in the recruitment will be on personal suitability.

Entry requirements

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.

A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Location: Solna

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

  • A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system.

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First day of employment According to agreement
Salary Scholarship
Reference number STÖD 2-3672/2022
Contact
  • Mikael Karlsson, mikael.karlsson@ki.se
Union representative
  • Henry Wölling, SEKO, henry.wolling@ki.se
  • Taher Darreh-Shori, SACO, taher.darreh-shori@ki.se
  • Carina Eklund, OFR, carina.eklund@ki.se
Published 19.Sep.2022
Last application date 02.Oct.2022 11:59 PM CEST

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