Do you want to contribute to understanding DNA repair in human health?

The Department of Oncology and Pathology’s mission is to improve diagnostics, treatment and quality of life for patients with cancer through basic, translational and clinical research and education in the field of cancer. We want to achieve excellence in research and education, foster clinical research and create high technology platforms for research support and innovation. In that we value ethics, high diversity and equality; cultivate openness networking and collaborations to consolidate national and international forces to cure cancer.

DNA Repair at Science for Life Laboratory

At Science for Life Laboratory, we establish platforms for the discovery of novel anti-cancer drugs and investigate molecular mechanisms in DNA repair and cancer metabolism. We work in teams combining experts in chemistry, biochemistry, biologists, pharmacologists, physicians and data scientists. An essential part of our work is research, teaching and collaboration on national, international and intradepartmental levels. Within this setting, the Helleday laboratory is seeking an Assistant Professor in Chemical Biology.

Your mission

The new Assistant Professor (Biträdande Lektor) will carry out research to establish a platform for the investigation of molecular functions and mechanisms of base excision repair members, particular DNA glycosylases. These efforts will enable the identification of novel targeting strategies to control DNA damage in cancer and high oxidative stress conditions. Thus, the applicant ideally combines a strong background in bioorganic synthesis (phosphates, carbohydrate, peptides), with expertise in assay development (biochemical and biophysical) and DNA repair biology with a particular focus on DNA glycosylases. Further, a profound knowledge of building computational model systems for molecular simulation is desired. The tasks of the post will further include:

• Applying for research funding
• Writing scientific publications
• Result Dissemination and Science Communication
• Supervision and Teaching of graduate and undergraduate level students (experience is merited)
• Participation in national, international and intradepartmental collaboration

The employment as Assistant Professor is time limited for 4 years with the right to apply for promotion to Senior Lecturer.

Eligibility requirements

Those eligible for employment as an Assistant Professor are individuals who have been awarded a PhD or attained equivalent research competence. Preference should be given to those who were awarded a PhD or attained equivalent research competence no more than five years prior to the expiry of the application period for the position as assistant professor.

Those who have been awarded a PhD or attained equivalent research competence earlier may however be considered if special grounds exist. 

Special grounds refer to:

• parental leave,
• positions of trust in trade union organizations
• mandatory service in the total defense forces
• long-term illness
• general medical internship (maximum 24 months)
• specialist medical residency for clinically active professionals (maximum 24 months).

Ground, dates and extent must be clearly specified in the application and verified with relevant documentation.

Bases of assessment

Scientific expertise will be most important when assessing applicants.

A person is eligible to be appointed if they have been awarded a Degree of Doctor or achieved the corresponding scientific competence and are able to demonstrate skills and experience in the fields of DNA repair, chemical biology or related. Preference will be given to candidates who have postdoctoral experience.

What do we offer?

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.

Your career continues here

Application

We prefer that Your application is written in English, but You can also apply in Swedish. An application must contain the following documents: Resumé, qualifications and description of planned research, presented in accordance with Karolinska Institutet’s qualifications portfolio.

Welcome to apply at the latest October 29.

The application is to be submitted through the Varbi recruitment system.

Particular assessment for promotion to Senior Lecturer

An Assistant Professor employed in accordance with the Higher Education Ordinance Chapter 4 Section 12a shall be promoted to Senior Lecturer if he or she is eligible for an employment as Senior Lecturer in accordance with the Instructions regarding the Appointment Procedure for Teachers at Karolinska Institutet and is assessed to be suitable for such employment in accordance with the assessment criteria that KI has decided should be applied when being promoted to Senior Lecturer. The assessment criteria stated in the Instructions regarding the Appointment Procedure for Teachers at Karolinska Institutet that was valid at the time of appointment as Assistant Professor will be applied when applying for promotion to Senior Lecturer. Current assessment criteria is found here. Such promotion results in a permanent position as Senior Lecturer.

Want to make a difference? Join us and contribute to better health for all