Postdoctoral Researcher in Mass Spectrometry Based Single Cell Proteomics

Do you want to contribute to top quality medical research?

Division of Physiological Chemistry I stems from the laboratory of Jöns Jacob Berzelius (1779-1848), the great Swedish scientist known for a variety of achievements. These include the discovery, together with his co-workers, of six new elements. Berzelius, the first Chemistry professor at KI, was an avid proponent of mass measurements, having published in 1818 a table of accurate weights of 45 out of the 49 known elements. Continuing Berzelius’ tradition, the Division bases its research on mass spectrometry. It also hosts two core facilities that perform proteomics analyses. One of the focal points of Division’s research is method development for proteomics.

Your mission

The candidate will participate in research concerning application in developments of single cell proteomics, which is an emerging area using bottom-up mass spectrometry based proteomics to characterize protein profiles of single cells. The goal is to develop further the establish a robust analytical workflow that will be applied to numerous biological problems, in which cellular heterogeneity plays a center role, such as cancer progression and cell differentiation. In addition, deep proteome profiling analytical methods will be applied to investigate viral infection mechanisms, utilizing sensitive multiplexing mass spectrometric workflows. The work is centered around the research program driven by the interdisciplinary scientific consortium, AROGYA, supported by the Swedish Research Council (Vetenskapsådet). The successful candidate will contribute to this groundbreaking research with experimental developments, performing and designing data analysis as well as presenting results in forms of scientific publications and presentations.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

The ideal candidate will have proven experience in analytical chemistry, proteomics and mass spectrometry. Good knowledge of spoken and written English is absolutely required as well as strong fundamental knowledge of bioinformatics and R programming skills are desired.

What do we offer?

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.

Location: Biomedicum, Solna

Application

An employment application must contain the following documents in English or Swedish:

A complete curriculum vitae (CV) with your qualifications, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
Verification from the thesis defense committee or the equivalent (only if the thesis defense is scheduled within six months after the application deadline)
A complete list of publications
A summary of current work (no more than one page) and a research statement
Contact details of two established researchers who agreed to serve as references

Welcome to apply at the latest 7th of November 2021.

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all