Do you want to contribute to top quality medical research?

Signal Transduction Laboratory, Rolf Luft Center for Diabetes and Endocrinology, Department of Molecular Medicine and Surgery, Karolinska Institutet.

Description of the subject area

One of our ongoing, long-term projects is the understanding of the beta-cell signalling machinery in vivo. It aims to gain in depth understanding of beta-cell function in vivo and possible changes in the signalling cascade under diabetic conditions. Most of the work is carried out using in vivo microscopy, which is complimented with animal physiology experiments and immunohistochemistry

Your mission

The Rolf Luft Center for Diabetes and Endocrinology is now recruiting a Research Specialist who will work in close collaboration with the rest of the team mainly on the generation mechanistic knowledge on beta-cell function and survival and to develop innovative therapeutic approaches in the field of diabetes and allotransplantation. The successful applicant will join and enhance ongoing efforts in beta-cell research, focusing on the physiology and pathophysiology in primary rodent and human islets of Langerhans in vivo.

Eligibility requirements

To be eligible for employment as a Research Specialist, in addition to holding a PhD in Pharmaceutical Sciences, Bio/Chemical Engineering, Immunology, Biochemistry, or related major field the applicant must have demonstrated experience in oligonucleotide chemistry, including aptamers, small interfering RNA, small activating RNA, miRNA or related field with an expressed interest in drug delivery.

Additional requirements:

  • Basic understanding of immunology, with an expressed interest in immunomodulation strategies
  • Demonstrated experience with either human on mouse islet biology
  • A basic understanding of in vivo imaging techniques is desirable
  • Self-initiative and ability to work independently as well as part of a cross-functional team
  • Excellent English proficiency (written and verbal) and project coordination skills

Assessment criteria

It is particularly meritorious that the applicant has shown

  • Competence in animal research

It is meritorious that the applicant has shown

  • Competence in aptamer selection strategies

After an overall assessment of the expertise and merits of the applicants in relation to the subject area, Karolinska Institutet will determine which of them has the best potential to contribute to a positive development of the activities at KI.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.


Location: Solna


Read more:https://ki.se/en/mmk/signal-transduction

Application

We prefer that Your application is written in English, but You can also apply in Swedish. An application must contain the following documents: Resumé, qualifications and description of planned research, presented in accordance with Karolinska Institutet's qualifications portfolio.

Welcome to apply at the latest 25 July 2021

The application must be submitted through the Varbi recruitment system.


Want to make a difference? Join us and contribute to better health for all

Type of employment Permanent position
Contract type Full time
First day of employment omg
Salary Månadslön
Number of positions 1
Working hours 100 %
City Stockholm
County Stockholms län
Country Sweden
Reference number STÖD 2-3260/2021
Contact
  • Per-Olof Berggren, Professor, per-olof.berggren@ki.se
Union representative
  • Virpi Töhönen, SACO, virpi.tohonen@ki.se
  • Taher Darreh-Shori, SACO, 08-524 835 29
  • Elisabeth Noren-Krog, OFR, elisabeth.noren-krog@ki.se
Published 30.Jun.2021
Last application date 25.Jul.2021 11:59 PM CEST

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