The Department of Biosciences and Nutrition performs research and education in several areas of medical science including aging, Alzheimer, biomaterial, molecular endocrinology, cancer biology, functional genomics, systems biology, epigenetics, structural biochemistry, bioorganic chemistry, immunology, and nutrition. It offers an excellent international research and working environment, including around 250 scientists, students, administrative and technical personnel. The Department resides in Neo at Campus Flemingsberg, a biomedical research building, aimed at being a creative and open environment that enables meetings, synergies, and exploration of areas of mutual interest across disciplines.

Do you want to contribute to top quality medical research?

Aging is one of the main risk factors for morbidity and mortality. Thus, a better understanding of the mechanisms that regulate this process is highly desirable. For this project, we focus on some of the most important aging regulators known to date, the FOXO family of transcription factors. Some members of this family reside downstream of the nutrient-sensing insulin/IGF signaling pathway and in response to low nutrients activates gene expression programs that slow down the aging process. FOXO transcription factors depend on a diverse range of binding partners and regulators to fulfill their roles, and we are elucidating their functions by biochemical, genetic, and cytological approaches. Much of this work is conducted in C. elegans, a very powerful model organism for aging research, but we combine these efforts also increasingly with work in human cell culture. (Please see Riedel et al., Nature Cell Biology 2013, Lin et al., Nature Communications 2018, or Sen et al., Nature Communications 2020, for examples of such recent work from our lab.)


Your mission

We are looking for a Postdoc to join our research group, the lab of Christian Riedel. Focus of this position is to explore an exciting new binding partner of FOXO transcription factors (TFs), which we found to be required for FOXO TFs to promote longevity in response to low nutrient signals. This work will be conducted both in C. elegans and in human cells. A substantial amount of preliminary data already exists, providing a good chance to bring this project to a high-impact publication already over the course of the next 2-3 years. For this work, you will synergize with aging biologists and a bioinformatician in our lab and also have the support of a larger aging-focused and well-equipment research environment at our department.

This position will be financed by a tax-free postdoc scholarship paid out by Karolinska Institutet. The scholarship position is initially offered for one year but can be extended. 

Your qualifications

We are looking for a talented and highly motivated scientist with a doctoral degree and strong background in Molecular Biology, Cell Biology, Genetics, and/or Biochemistry. Good expertise in either C. elegans methods or in mammalian cell culture techniques is desired. Also, a background in the biology of aging is appreciated, even though it is not essential.

Applicants are expected to work independently but as part of an enthusiastic team and to be proficient in English. They are expected to play a leading role in the design and execution of their experiments as well as the analysis and the presentation/publication of the resulting data.

Entry requirements

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. Persons who are resident in Sweden and/or have carried out all or part of their academic education at KI or some other educational institution in Sweden cannot be considered for scholarships from KI. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.

A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.

To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the postdoctoral education. 

The head of the department determines whether the applicant’s previous training and scholarly qualifications correspond to a Swedish doctorate or (higher).

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all.

Location: Department of Biosciences and Nutrition, Neo Building, Flemingsberg

Links: https://ki.se/en/bionut/department-of-biosciences-and-nutrition

          http://riedellab.org/

          https://ki.se/en/bionut/christian-riedel-group   


Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English:

  • A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)


You are welcome to apply at the latest by 17 May 2021. The application is to be submitted on the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Reference number STÖD 2-1941/2021
Contact
  • Christian Riedel, PI, +46-73-670 70 08
  • Thomas Tinglöv, Head of Administration, +46-8-524 835 49
Union representative
  • Henry Wölling, SEKO, +46-8-524 840 80
  • Anders Lindholm, OFR, +46-8-524 810 12
Published 23.Apr.2021
Last application date 17.May.2021 11:59 PM CET

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