Do you want to contribute to better health for all?

In the division “Receptor Biology & Signaling” headed by Prof Gunnar Schulte, G protein-coupled receptors and particularly Class F receptors are in focus. The work aims to better understand how ligands interact with Class F receptors, how conformational changes are established to activate the receptors and consequently to initiate interaction and activation of intracellular signaling components. Functional selectivity of Class F receptors towards heterotrimeric G proteins or other pathways are analyzed with the hope to exploit the novel knowledge therapeutically.
For more information: https://ki.se/en/fyfa/schulte-lab 

Your mission

The research project is aiming to understand underlying molecular details of Class F receptor activation for future drug development. It is embedded in the EUbOPEN project (https://www.eubopen.org/), which provides the integration of the project into medicinal chemistry, chemogenomics, compound identification and validation, drug discovery, and structural biology. The highly motivated candidate, with a strong background in medicinal chemistry and GPCR pharmacology, is expected to drive the research project, technical development and concept development from idea to publication. The candidate’s broad expertise in wet laboratory and assay development is expected to serve as a resource for the research team. The candidate will participate in supervision of masters and PhD students. In addition to lab work, the applicant is expected to take an active, constructive and developing part in lab management.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

The applicant should have a profound background in medicinal chemistry, biochemistry, molecular biology, and cell biology with emphasis on GPCR pharmacology. Solid experience in cell culture, protein biochemistry, resonance energy transfer-based (FRET/BRET) techniques, ligand binding experiments, cloning, assay design and assay validation are required. Documented experience (previous high quality publications) with GPCR pharmacology and protein biochemistry is a requirement.

What do we offer?

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.


Location: Solna Campus, Biomedicum

Application

An employment application must contain the following documents in English or Swedish:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)
  • A cover letter

The application is to be submitted through the Varbi recruitment system.
Welcome to apply! 

Want to make a difference? Join us and contribute to better health for all

Type of employment Temporary position longer than 6 months
Contract type Full time
First day of employment Upon agreement
Salary Monthly salary
Number of positions 1
Working hours 100%
City Solna
County Stockholms län
Country Sweden
Reference number STÖD 2-729/2021
Contact
  • Gunnar Schulte, professor, gunnar.schulte@ki.se
Union representative
  • Henry Wölling, SEKO, henry.wolling@ki.se
  • Helin Norberg, SACO, helin.norberg@ki.se
  • Niklas Andersson, OFR, niklas.andersson@ki.se
Published 15.Feb.2021
Last application date 28.Feb.2021 11:59 PM CET

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