Do you want to contribute to top quality medical research?

Our research program is structured in 3 main areas: 1) cardiovascular aging; 2) effects of gene-environment interaction in the vessel wall; 3) impact of gene dysregulation on cardiovascular outcomes in obese and subjects with type 2 diabetes. The impact of this program is outlined by the notion that prevalence of these conditions is alarmingly increasing worldwide.

Although advances in therapy have reduced morbidity and mortality, cardiovascular risk is far to be eradicated and mechanism-based therapeutic approaches are in high demand. Furthermore, our program also aims to understand the link between environmental factors, metabolic disease and premature cardiovascular aging. These objectives are accomplished by a translational approach focused to characterizing cardiovascular phenotypes through novel technologies, genetically-engineered animal models and clinical studies.

The candidate contributing to decipher novel molecular networks of cardiovascular disease will be instrumental to develop effective diagnostic and therapeutic strategies.

Your mission

The position focuses on the molecular and cellular processes underlying vascular and cardiac dysfunction in the context of obesity, diabetes and associated metabolic disease. A major part of the project will be to identify detrimental epigenetic signatures eliciting oxidative and inflammatory changes.

Your profile

Applicants must hold a PhD in Biomedicine (or an equivalent scientific degree), be highly motivated, independent and senior enough to organise the work of biological or medical doctoral students and integrate themselves into a team. A background in molecular biology with a track-record in ChIP assay, gene profiling of chromatin modifying enzymes and/or in ex-vivo animal studies (e.g. organ chamber experiments) with Felasa Licence for handling small animals (mice/rats) is required. Previous experience in basic and translational studies on cardiovascular research is an advantage.The candidate will work in an international and highly motivated surrounding. Proficiency in English, both spoken and written is mandatory. The position is initially limited to 1-2 year(s) but prolongation after evaluation is possible. 

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

What do we offer?

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.

Location

The position is located within the Department of Medicine, Solna. The department consists of twelve units and each division consists of several research groups. The position is located within the Cardiology Unit. The group consists of a team of physicians and scientists focused on studying the molecular and cellular processes underpinning vascular and cardiac dysfunction in the context of diabetes. Key aspects of the research program also include the link between environmental factors, metabolic disease and premature cardiovascular ageing. These objectives are accomplished by a translational approach aimed to characterize cardiovascular disease phenotypes through novel technologies, genetically-engineered animal models and human studies.

 

--- [Video about a Karolinska Institutet, how we work towards "a better health for all"] --

Application

An employment application must contain the following documents in English or Swedish:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)
 

The application is to be submitted through the Varbi recruitment system.

 

Want to make a difference? Join us and contribute to better health for all

Type of employment Temporary position longer than 6 months
Contract type Full time
Number of positions 1
Working hours 100%
City Stockholm
County Stockholms län
Country Sweden
Reference number STÖD 2-499/2021
Contact
  • Francesco Cosentino , 08-517 75 398 e-mail: francesco.cosentino@ki.se
Union representative
  • Bruna Gigante, SACO, bruna.gigante@ki.se
  • Afsar Rahbar OFR, Afsar.Rahbar@ki.se
  • Louisa Cheung, SACO, Louisa.Cheung@ki.se
Published 01.Feb.2021
Last application date 28.Feb.2021 11:59 PM CET

Tillbaka till lediga jobb