Do you want to contribute to top quality medical research?

The Department of Medicine, Solna, is one of the largest departments at Karolinska Institutet. The department consists of several units that are separated into different research groups. The core activities of the department are research, doctoral education and undergraduate education for medical and biomedical students. The research has three main profiles: allergy, cardiovascular medicine and inflammatory diseases.]

Division

The successful candidate will work in the wound healing research group headed by Dr. Ning Xu Landén (www.xulandenlab.com). The group belongs to the Dermatology and Venereology Division, Karolinska University Hospital Solna and the Ming Wai Lau Centre for Reparative Medicine (MWLC), and is physically located at the Centre of Molecular Medicine (CMM; https://www.cmm.ki.se/). The research is performed in an interdisciplinary setting with strong collaboration with clinical departments and other national and international research groups. The group has extensive experience in non-coding RNA research with well-established methodologies for studying the expression and function of non-coding RNAs in skin wound healing.

Duties

The chronic non-healing wound is a common and severe medical problem with unclear pathogenesis. The discovery of non-coding RNAs (ncRNAs) as powerful gene regulators provides hope in the quest to develop novel RNA-based treatments for a wide variety of diseases; however, the role of ncRNAs in human skin wound healing remains largely unexplored. We aim to reveal the expression and functional signatures of ncRNAs (primarily focusing on microRNAs, circular RNAs, and long ncRNAs) in human skin wound healing, and to identify ncRNAs that may be targeted in wound therapy. The current method spectrum of the group is centered around bioinformatics, molecular biology, cell biology, and biochemistry with human cells and tissues as well as mouse models but will be expanded.

The task of the postdoctoral researcher will include study design, experiments, analysis and presentation of research data in the form of scientific publications, grant applications and at meetings and conferences, as well as supervision of students. We offer an intellectually stimulating and welcoming working environment, and we look for a talented and motivated co-worker to develop our next breakthrough ideas.

Entry requirements

Required skills of the successful candidate are:

  • A PhD or in exceptional cases expected to obtain soon, in the area of molecular biology, cell biology or biochemistry.
  • Extensive experience with tissue culture, molecular and biochemical techniques.
  • Extensive experience in RNA biology or skin biology research.
  • Ability to deliver high-quality scientific outputs with a strong publication record.
  • Good interpersonal skills and the ability to work both independently but also as a part of a large team.
  • Good knowledge of spoken and written English and good communication skills.

 

We will look favorably upon if the candidate has experiences in one or more of the following areas:

  • Biochemical approaches to study the interaction of RNA, protein, and DNA.
  • Animal models
  • Histology techniques such as in situ hybridization and immunohistochemistry
  • Flow cytometry
  • Single-cell transcriptomics
  • High-throughput screen
  • Method development.

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Location

The position is located within the Department of Medicine, Solna. The department consists of twelve divisions and each division consists of several research groups. The position is located within the research group of Associate Professor Ning Xu Landén (www.xulandenlab.com).

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

  • A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Reference number STÖD 2-403/2021
Contact
  • Ning Xu Landén , / 0762345626
Union representative
  • Bruna Gigante, SACO, bruna.gigante@ki.se
  • Louisa Cheung, SACO, Louisa.Cheung@ki.se
  • Afsar Rahbar OFR, Afsar.Rahbar@ki.se
Published 27.Jan.2021
Last application date 24.Feb.2021 11:59 PM CET

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