Do you want to contribute to top quality medical research?

We are a research group studying non-coding RNAs in epidermal homeostasis and carcinogenesis using a combination of patient material, state-of the-art in vitro and in vivo disease models. The successful applicant will have the opportunity to be part of a team with an enthusiasm for science and a longstanding interest in non-coding RNA biology and in the skin.

Your mission

The successful candidate will be responsible to design and perform in vitro and in vivo mechanistic experiments to dissect the role of non-coding RNAs in skin cancers and epithelial cell differentiation.

The project includes studies on primary cell cultures, patient samples and mouse models of skin cancer, such as tumor xenograft models. The methods we use are molecular biology techniques with a special emphasis on non-coding RNA biology using antisense and CRISPR-based systems to study non-coding RNA-function, in cell culture and 3D skin models, and to an increasing extent, data analysis with bioinformatics methods. We have more than a decade of experience with skin biology and non-coding RNA research which creates a unique combination.

The main duties of the successful candidate will be:

  • Designing, performing and establishing state-of-the-art in vitro and in vivo assays
  • Overall responsibility for the research project, including following relevant literature and identifying and communicating need for further development
  • Writing scientific articles
  • Supervision of junior researchers/students
  • Presenting results on scientific congresses

Your profile

We are looking for a researcher with a genuine interest in medical research, molecular biology and problem solving.

The candidate should possess a PhD degree in a relevant scientific discipline (e.g. biomedicine, molecular biology, pharmacy, medicine). Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

The successful candidate has a genuine interest in research and an inner drive to understand biological problems. The candidate is expected to use a wide range of molecular biology methods for the characterization of relevant pathways in primary cells, patient samples and animal models such as RNA interference and CRISPR/Cas9-based gene editing. Experience with, and a deep understanding of molecular biology techniques and cell culture is a requirement. Experience with animal models related to skin cancer is not a requirement but meritorious. Experience in non-coding RNA research is not a requirement but meritorious.

The work requires a good collaboration ability, the ability to solve problems and openness to learn new methods. An excellent knowledge of English language, both oral and written, is required. Key criteria:

  • Relevant scientific competence and skills
  • Relevant work experience
  • Personal suitability 
  • Language skills and communication skills
  •  

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Location

The position is located within the Department of Medicine, Solna. The department consists of twelve divisions and each division consists of several research groups. The position is located within the research group Pivarcsi (https://www.cmm.ki.se/sv/web/guest/andor-pivarsci-group, located at the Center for Molecular Medicine (CMM, cmm.ki.se). The Pivarcsi-group has a close collaboration with other dermatology research groups that are located in CMM. CMM offers also core facilities and opportunities to collaborate with other translational research groups. The proximity of CMM to the New Karolinska Hospital allows for collaboration with clinicians at the dermatology clinic which is a prerequisite for translational projects.

--- [Video about a Karolinska Institutet, how we work towards "a better health for all"] -

Application

An employment application must contain the following documents in English or Swedish:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)
 

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Type of employment Temporary position 3-6 months
Contract type Full time
Number of positions 1
Working hours 100%
City Stockholm
County Stockholms län
Country Sweden
Reference number 2-3729/2020
Contact
  • Andor Pivarcsi, andor.pivarcsi@ki.se
Union representative
  • Bruna Gigante, SACO, bruna.gigante@ki.se
  • Louisa Cheung, SACO, Louisa.Cheung@ki.se
  • Afsar Rahbar OFR, Afsar.Rahbar@ki.se
Published 07.Sep.2020
Last application date 21.Sep.2020 11:59 PM CET

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