Karolinska Institutet, Department of Cell and Molecular Biology, Höög

Do you want to contribute to top quality medical research?

The Department of Cell and Molecular Biology (CMB) is a department with a strong focus on basic science. CMB conducts research and education in cell biology, molecular biology, developmental biology, stem cell biology, cancer and infection biology.

Your mission

The position is placed in the research group of Christer Höög at the Department of Cell and Molecular Biology, Karolinska Institutet. We study various aspects of oogenesis and spermatogenesis using mouse genetic models. The central scientific interest is to understand the division of female germ cells, with a special focus on mechanisms involved in age-related aneuploidy in mouse and human eggs.

We are seeking a highly motivated and enthusiastic researcher with a strong background in developmental biology with a practical experience in manipulating mouse female germ cells and eggs. The approaches will include a broad range of biochemical, genetic and microscopic techniques to study chromosome segregation in female eggs, including super-resolution microscopy. The applicant will be responsible for setting up and organizing the project and supervising direct reports as well as PhD students and/or technical stuff.

Your profile

A person is eligible to be appointed Researcher if he or she has been awarded a Degree of Doctor or has achieved the corresponding scientific competence, as well as documented research after publicly defending his or her doctoral thesis corresponding to qualification as Assistant professor.

The candidate should hold a PhD in Molecular Biology, have an education in physical/biophysical area and a strong background in developmental biology, with the preference to a prior work in meiosis in relation to the meiotic synaptonemal complex and meiotic divisions with a strong publication records in these fields. The candidate should have an extensive training in handling germ cells, including spermatocyte and oocyte isolation at various developmental stages, oocyte microinjections, fixation and basic biochemical techniques. Knowledge and experience in fluorescent microscopy, live imaging microscopy, image analysis and image data processing of the germ cells is required. The candidate needs to have experience in statistical analysis, R, MatLab, Imaris and ImageJ software. The position will demand to work with mice animal models, so practical experience in handling mice and the FELASA C or corresponding certificates are the merits.

Since the position includes many international contacts and the unit has staff from all over the world the candidate should be fluent in English (both spoken and written), and demonstrate excellent communication skills, documented by participation in international meetings. The basic knowledge of Swedish is a merit. The successful candidate must have a strong analytical ability as well as be well organized. The candidate’s personal skills will be highly valued. Qualified candidates should have a prior teaching experience.

Bases os assessment

We stress research expertise when assessing applicants.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Location: Solna


An application must contain the following documents in English: Resumé, qualifications and description of planned research, presented in accordance with Karolinska Institutet's qualifications portfolio.

Welcome to apply at the latest xxx

The application is to be submitted through the Varbi recruitment system.  

Permanent position are initiated by a six months trial period.

Want to make a difference? Join us and contribute to better health for all

Type of employment Tillsvidareanställning
Contract type Full time
Number of positions 1
Working hours 100 %
City Stockholm
County Stockholms län
Country Sweden
Reference number 2-5929/2019
  • Prof. Christer Höög, christer.hoog@ki.se
Union representative
  • Magnus Anå, OFR, 08-524 864 37, magnus.ana@ki.se
  • Biborka Bereczky Veress, SACO, 46 70-173 85 75
  • Elisabeth Valenzuela, SEKO, 08-524 863 53
Published 02.Dec.2019
Last application date 19.Dec.2019 11:59 PM CET

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