Karolinska Institutet, the Department of Medicine, Huddinge

Department of Medicine, Huddinge
The Department of Medicine, Huddinge, conducts preclinical and clinical research in a variety of areas and undergraduate and graduate education. The department is internationally oriented and consists of seven units with a total of nearly 60 research groups, including three research centres.

Division
The Division of Infectious Diseases conducts preclinical, translational, and epidemiological research projects. The laboratory is located within the newly build facilities at Alfred Nobels Allé 8 (ANA Futura Laboratory), Campus Flemingsberg. The announced position will be placed in Professor Anders Sönnerborgs research group, which has a strong focus on pathogenesis, antiretroviral treatment, including HIV drug resistance, and cure of HIV infection. The experimental research is focused on the interaction between HIV and antiretroviral drugs as well as mechanisms of viral latency.

Duties
The present position research assistant aim towards proteo-transcriptomics studies to develop and execute novel bioinformatics and statistical methods for transcriptomics, proteomics, and multiparametric proteotranscriptomics analysis to identify biomarkers and map the intercellular pathway of natural control of HIV infection, as well as the importance of the gut microbiota for viral persistence and pathogenesis. The candidate should have a strong background in bioinformatics. Experience of analysis of immune-metabolism more specific to nucleotide synthesis, mitochondrial DNA depletion, and cellular metabolic pathways are of great value.

Mastery of the core concepts of Bioinformatics more specific towards the integrative omics is expected. These include (a) advanced methods in computational biology towards the machine learning in medical science, (b) knowledge and awareness of the basic principles and concepts of biology, computer science and mathematics, (c) the design and implementation of relational databases, and (d) the construction of predictive mathematical models of biological systems. The research assistant is expected to analysis large amount of omics data mainly transcriptomics and proteomics.

Entry requirements
The candidate must hold a Masters Degree in the field of systembiology. We seek a highly motivated candidate with a demonstrated record of scientific excellence.  

The candidate should also have:

  •  Second-cycle background in genetics and/or bioinformatics.
  • Interest and prior experience in transcriptomics and mass-spectrometry based proteomics analysis are essential. Provide github account details.
  • Strong competence in Python, R-programming language and network analysis (e.g. Cytoscape). Preferences will be given who have experience in protein structure analysis.
  • Be able to work well in a multidisciplinary team, as well as having the ability to work independently.
  • Possess good organizational skills and know how to multitask.

We welcome a creative, hardworking and enthusiastic team-player to our group. The candidate is expected to take part in experimental design, experimentation, presentations, and preparation of publications. The candidate should be proficient in English, both spoken and written. The successful candidates will be expected to actively seek funding with the assistance of the PI.

Application process
An employment application must contain the following documents in English or Swedish:

  1. A complete curriculum vitae, previous academic positions, academic title, current position, academic distinctions, and committee work
  2. A complete list of publications
  3. A summary of current work (no more than one page)
  4. Verifications for crediting of illness, military service, work for labor unions or student organizations, parental leave or similar circumstances

he application is to be submitted through Varbi recruitment system.

Type of employment Visstidsanställning längre än 6 månader
Contract type Full time
Number of positions 1
Working hours 100 %
City Huddinge
County Stockholms län
Country Sweden
Reference number 2-4376/2019
Contact
  • Anders Sönnerborg, Anders.Sonnerborg@ki.se
Union representative
  • Belinda Pannagel, SACO, belinda.pannagel@ki.se
  • Carina Eklund, OFR, carina.eklund@ki.se
Published 03.Sep.2019
Last application date 13.Sep.2019 11:59 PM CET

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