Postdoctoral studies in pre-clinical studies of ADP-ribosylation - Hiring in process/Finished, not possible to apply

Research Group
ADP-ribosylation is a post-translational modification of proteins and chemical modification of nucleic acids, and is involved in essential regulatory processes.

The Schüler team (https://ki.se/en/bionut/schuler-team) studies the enzymes and binder domains that modulate ADP-ribosylation, and develops and evaluates inhibitors of these proteins. They use a variety of approaches including cell biology, biochemistry and structural biology to address important questions about how modulators of ADP-ribosylation can be used for therapeutic purposes the areas of cancer and infection.

Duties
We are looking for a Postdoctoral fellow which will be financed by a scholarship. The postdoc will carry out a research project using human cell lines. Furthermore the candidate will be responsible for analysis of changes in protein modification patterns following inhibition of PARP enzymes, as well as analysis of the molecular basis underlying these changes.

Qualifications
We are looking for a person with solid experience of laboratory work using biochemistry, molecular biology, and bioinformatics. Practical experience of recombinant protein production, cell culture, and bioactive organic compounds are a requirement. Previous practical experience with ADP-ribosylating and de-ADP-ribosylating enzymes, first-author publications in this research area in international peer-reviewed journals, as well as personal scholarships and awards received in competition are considered a merit. Good communication and writing skills in English are required.

Entry requirements
Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Type of scholarship
The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process
An application must contain the following documents in English or Swedish:

• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications and a description of the applicant’s role in each publication
• A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system.