Karolinska Institutet, Department of Medical Biochemistry and Biophysics, Vascular Biology

The lab and technologies
The Jakobsson lab investigates processes of blood vessel morphogenesis and function in development and disease, with the aim to develop new therapies. The lab utilizes mouse models of human disease based on inducible genetic loss- and gain- of-function in combination with state-of-the-art confocal live imaging (multi-photon, in vivo and ex vivo). In addition the environment provides access to drug screening platforms, proteomics and single cell RNA sequencing. The lab has an extensive international scientific network and is integrated in a highly interactive scientific environment with close contact with the clinic. Recent publications from the lab: Jin et al,Nat. Cell Biol.,2017  Wang et al, Development, 2017, Wang et al, Sci. Rep., 2018

The project
The lab aims to find novel ways of modulating angiogenesis and vessel function. The studies build on the lab’s previous findings on endothelial cell- signalling, behaviour and gene expression in vascular patterning and malformation in the CNS. The project will focus on mechanisms of establishment of arteries and veins and maintenance of vessel function in relation to human disease. Data acquisition is facilitated by novel mouse models in combination with abovementioned technologies, including single cell RNA seq. Please visit the lab website (http://ki.se/en/mbb/lars-jakobsson-group) for an overview.

The Department and location
The Department of Medical Biochemistry and Biophysics with its 450 employees conducts biomedical research and education at the absolute forefront. The postdoc will work in Dr. Lars Jakobsson’s group at the Division of Vascular Biology, in a vibrant new research center, Biomedicum, in central Stockholm. Please see Biomedicum Stockholm

Qualifications To qualify, the applicant must hold (or shortly obtain) a doctor’s degree, acquired no later than two years prior application deadline, in the fields of molecular/ developmental biology, biotechnology/ engineering or similar. Please see the full advertisement for further details requirement.

Entry requirements
Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Type of scholarship
The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process
An employment application must contain the following documents in English or Swedish:

  • A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system.

Working hours 100%
City Stockholm
County Stockholms län
Country Sweden
Reference number 2-568/2019
Contact
  • Lars Jakobsson, +46 8 524 871 24
Union representative
  • Biborka Bereczky Veress, SACO, 46 70-173 85 75 , biborka.bveress@ki.se
  • Anne Edgren, OFR/S, P, O, 08-524 87570
  • Henry Wölling, SEKO, henry.wolling@ki.se
Published 25.Jan.2019
Last application date 25.Feb.2019 11:59 PM CET

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