Karolinska Institutet

Karolinska Institutet, The Depertment of Medicine, Huddinge
Established in June 2013, the Karolinska Institutet/AstraZeneca Integrated Cardio Metabolic Centre (KIAZ ICMC) represents a unique and exciting opportunity for academic scientists to collaborate and work side-by-side with scientists from the pharmaceutical industry to discover and develop the next generation of medicines to treat cardiovascular and metabolic diseases. More information about AZ/KI ICMC can be found at http://ki.se/en/medh/integrated-cardio-metabolic-centre-icmc

Description of the research group
The central scientific interest of the Prof. Chien lab is to understand heart development at the molecular and cellular level, with the ultimate goal of applying the developmental principles, logic, pathways, technology, and model systems to unravel human heart disease. We use several different approaches to study heart development, including in vitro stem cell differentiation system and in vivo embryo development studies. 

Responsibilities
We are seeking a lab manger with an extensive background in experimental laboratory work.

In addition to the entry requirements, the candidate will be responsible for organizing the common resources at the center, including supervising and improving lab work. You will work closely with researchers and assist in the introduction of the laboratory for new staff, guest researchers and graduate students as well as with the development and improvement of experimental methods. 

Entry requirements
• Previous experience working with mice, with at least a FELASA B certificate or equivalent
Experience with writing ethical applications in Swedish for animal research and managing contacts with ethical boards and authorities
• Excellent in vitro laboratory skills including
molecular cloning as well as protein production and analysis (i.e. Western blotting and ELISA) techniques.
• Histology, immunohistochemistry and cryosectioning experience
• Experience in training people
• Ability to create and maintain the chemical and biological database
• Ability to maintain good relationship with the department and animal facility as well as with external collaborators
• Supervision of lab members
• Support of all the projects in the lab
• Strong ability to negotiate with sales representatives
• Excellent organizational skills
• The applicant must speak and write fluent English and Swedish and display excellent communication skills 

Meriting
• Administration and management skills
• Previous experience in managing a medical research laboratory
• Emphasis will be placed on personal qualities as responsibility, flexibility, teamwork and ability to solve problems.
• Previous knowledge of the following techniques is meriting;
production of libraries for single cell RNA sequencing and production of modified mRNA. 

Application process
The application must contain the following documents in Swedish or English:
- A personal letter
- Curriculum vitae 
- Three letters of reference
The application is to be submitted through the Varbi recruitment system.

At Karolinska Institutet a 6-month trial period is required for all permanent appointments.

Type of employment Permanent position
Contract type Full time
First day of employment As soon as possible
Salary Månadslön
City Stockholm
County Stockholms län
Country Sweden
Reference number 2-4364/2018
Contact
  • Katarina Drakenberg, katarina.drakenberg@ki.se
Union representative
  • Yvonne Edlund OFR/ST , yvonne.edlund@ki.se
  • Mats Rudling, SACO, mats.rudling@ki.se
Published 17.Aug.2018
Last application date 26.Aug.2018 11:59 PM CEST

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