Research assistant – Understanding skeletal muscle insulin sensitiv - Under tillsättning eller tillsatt, ej sökbar

Research group
The division of Integrative Physiology at the Department of Molecular Medicine and Surgery  at Karolinska Institutet is seeking a highly motivated research assistant to join the group of Professors Juleen Zierath and Anna Krook and to identify and determine the physiological role of new targets altered in Type 2 Diabetes. The candidate will join our research group and work on projects focused on the identification and biological validation of key regulatory metabolic pathways and molecules that contribute to the development of insulin resistance in Type 2 Diabetes. https://ki.se/en/mmk/integrative-physiology

Task
The project will focus on identification of molecular changes in skeletal muscle contributing to altered metabolism in subjects with type 2 diabetes. Projects will examine effects of exercise as well as diet interventions, with the aim to identify key molecular events regulating metabolic adaptation /maladaptation.  The effect of candidate molecules will be further studied in cell culture and model organisms

Qualifications
We seek an enthusiastic and talented person with suitable molecular biology and/or human physiology education with interest and experience in metabolic disease and molecular biology. A thorough background in physiology and metabolism, in particular human metabolism, is required, Experience of work involving patient exercise interventions is an advantage, as is previous experience of molecular biology and Cell culture techniques. Determination of skeletal muscle exercise adaptations and associated metabolism is also desirable.

Important personal qualifications are curiosity, engagement and social competence. Documented experience of coordinating projects is qualifying, as well as scientific publications and other working experience in research. Excellent knowledge in English, in speech and written, is a prerequisite. We use English in all activities in the group.