Department of Medicine, Solna, Immunology and Allergy division

The Department of Medicine, Solna, is one of the largest departments at Karolinska Institutet. The department consists of several divisions that are separated into different research groups. The core activities of the department are research, doctoral education and undergraduate education for medical and biomedical students. The research has three main profiles: allergy, cardiovascular medicine and inflammatory diseases.

We are seeking a computational biologist at post-doctoral level (or with at least 4 years of post-graduate experience) to work with the team of Dr. Eduardo J. Villablanca and Dr. Nicola Gagliani at the Department of Medicine (MedS) at Karolinska Institutet, Stockholm, Sweden.

Division
The Immunology and Allergy Unit at the Department of Medicine, Solna performs research on different aspect of allergy and autoimmune diseases. Our research group (PI: Eduardo Villablanca) will investigates the molecular and cellular mechanisms underlying the establishment of intestinal homeostasis and how breakdown of these mechanisms might lead to inflammatory bowel diseases (IBD). Our group works in an inspiring and interactive research environment at the Karolinska University, Solna and has ongoing collaborative projects with national and international colleagues. To tackle these questions, Eduardo’s and Gagliani’s teams are using Single Cell RNA-Sequencing among other array and sequencing based approaches to analyze immune responses in vivo.

Duties
We are seeking a Computational Biologist at post-doctoral level for a 24-48 months project. The main duties include bioinformatics analysis with particular focus in RNA-seq and single cell RNA-seq analysis. An interest in data visualization and big data analysis is a plus. The applicant is expected to have a strong interest in mucosal immunology. The applicant will work in close collaboration with other PhD students, postdocs and researchers. The applicant is expected to actively participate in other lab projects and present results to general and specialized audiences. An interest in the application of machine learning approaches is also desirable.
The duties also include: 
Data QC, data management and archival storage Analysis of large datasets, preparation of codes, development of new methods/tools for advanced analysis of datasets Support the ongoing research in the group, help write papers, grants and scientific meeting presentations Shape, develop and maintain the current computing resources of the group.

Entry requirements
The successful candidate has a solid background in bioinformatics, statistics and computational biology, good expertise in statistical and bioinformatics software, and an ability to work in a multidisciplinary research environment. The individual should be highly motivated and be able to work independently, while being able to communicate effectively with other members of the team.
Preferably, the candidate should hold a PhD degree (or complete one within the next 2 months) or have a track record of performing independent research over the past 4 years. A proven publication record in well-regarded journals is also advantageous. Outstanding programming skills in at least R, Matlab, Python, Perl or other mathematical software/programming languages is required.

Requirements: Qualified candidates should have:

  • A Ph.D. or M.D./Ph.D. in immunology or computational biology.
  • Outstanding creative thinking, problem solving, motivation, persistence as well as personal initiative and communication skills
  • Independent work at the laboratory as well as extensive collaboration with clinicians and other experimental groups.
  • Excellent molecular and cell biology as well as microbiology skills and strong background in mucosal immunology
  • Strong publication record in peer-reviewed journals
  • Fluency in both oral and written English is necessary

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence.

Application process
An employment application must contain the following documents in English or Swedish:

  1. A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  2. A complete list of publications
  3. A summary of current work (no more than one page)

The application is to be submitted through the Varbi recruitment system.

Type of employment Temporary position
Contract type Full time
Number of positions 1
Full-time equivalent 100
City Solna
County Stockholms län
Country Sweden
Reference number 2-3302/2018
Contact
  • Eduardo Villablanca, 073-628 22 89
Union representative
  • Lars Ährlund-Richter, SACO, 08 - 5177 34 50, lars.ahrlund@ki.se
  • Niklas Andersson, OFR, niklas.andersson@ki.se
Published 12.Jun.2018
Last application date 30.Jun.2018 11:59 PM CEST

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