Postdoctoral researcher in B cell biology in rheumatic diseases

Do you want to contribute to top quality medical research?

The Department of Medicine, Solna, is one of the largest departments at Karolinska Institutet. The department consists of several divisions that are separated into different research groups. The core activities of the department are research, doctoral education and undergraduate education for medical and biomedical students. The research has three main profiles: allergy, cardiovascular medicine and inflammatory diseases.

Your mission

We seek a cell biologist/immunologist motivated to work in translational research in the field of autoimmunity. The current project aims to produce monoclonal antibodies, characterize them and to understand their role in disease. Key tasks involve the use of B cell repertoire sequencing using primary cells from patients with autoimmune myositis and healthy donors, antibody engineering, affinity chromatography, transfection of cell lines, ELISA and cell culture including myoblasts and myotubes. All work will be performed within the multidisciplinary research group of Professor Ingrid Lundberg at the Center for Molecular Medicine (https://ki.se/personer/ingrid-lundberg) in close collaboration with the research group of Associate Professor Caroline Grönwall (https://ki.se/en/research/groups/b-cells-and-autoantibodies-in-rheumatic-disease-team-caroline-gronwall). The candidate will also be involved in several collaborations both nationally and internationally.

Your profile

PhD in biology or comparable with focus on B cell immunology and autoimmunity. Previous experience on producing monoclonal antibodies is beneficial. The candidate should have experience in ELISA, western blot, multi-color flow cytometry and affinity chromatography. Experience form cell culture work including myoblasts and myotubes is a strength.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a Swedish doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialties and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location

The position is located within the Department of Medicine, Solna. The department consists of eleven divisions and each division consists of several research groups. The position is located within the research group of Prof. Ingrid Lundberg at the Center for Molecular Medicine https://ki.se/en/people/ingrid-lundberg,
https://ki.se/meds/reumatologi

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Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted through the Varbi recruitment system.

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