Postdoctoral scientist in platelet research to HERM / NEO - Hiring in process/Finished, not possible to apply

Do you want to contribute to top quality medical research?

The Center for Hematology and Regenerative medicine, HERM, is a research unit within the Department of Medicine Huddinge with a focus on translational hematology and immunology. HERM is in the NEO building and consists of a mix of clinical and preclinical research groups, each with a focus on clinically relevant questions in hematology, stem cell biology and immunology, including basic immunology, immunodeficiency and transfusion immunology.

Recruiting research group

Professor Petter Höglund leads a translational immunology group with a focus on natural killer (NK) cells, platelets and neutrophils. See https://ki.se/en/medh/petter-hoglund-group for more information. The group is now looking for a postdoctoral scientist to study platelet biology in healthy individuals and in patients with various diseases.

Platelets are easily activated by experimental handling and new techniques are needed to overcome this hurdle. The task of the project is therefore to take platelet research to the next level. Novel multicolor flow cytometry panels are needed in which combinations of markers for function and phenotype can be included. In addition, the task is to develop new methods for platelet function, in which single platelets and platelets in bulk conditions can be assayed, testing the hypothesis that subsets of platelets with differential functions, specifically hyperfunctional platelets, exist and have unique biological roles.

Your mission

The main responsibility will be to develop and conduct independent research projects at the postdoctoral level. The candidate is expected to bring new knowledge in how to study platelets and also to support ongoing platelet projects. Apart from platelet-specific methods, laboratory work in the group includes all aspects of an immunology lab, such as molecular biology and cell culture.

Your profile

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

Applicants must have adequate university education in biomedicine or cell biology. The candidate must have a PhD or a foreign degree deemed to be equivalent to a doctoral degree is required. The successful candidate is very well-organized, responsible, collaborative and likes to work in a dynamic environment with diverse tasks.

The applicant should demonstrate practical experience in molecular biology, cell biology and flow cytometry techniques. For the latter, advanced knowledge regarding multicolor FACS analysis of platelets is a requirement, and experience with various methods, traditional and novel ones, to study platelet function is necessary. Bioinformatics experience is a merit, to facilitate analysis of large datasets in flow cytometry and to prepare for experiments using transcriptional profiling of platelet subsets. Good collaborate skills, independence, communication skills and computer skills are required.  Good knowledge in written and spoken English is required.

Type of position

The employment will be in the form of a postdoctoral position for two years.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Flemingsberg

Choose to work at KI – Ten reasons why

Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• Personal letter
• A complete list of publications
• A summary of previous work experience (no more than one page)
• A summary of qualifications in terms of methods with detailed description of the level of knowledge with examples. This is particularly important when it comes to work with flow cytometry and experimental animals but will also facilitate evaluation at large.

Welcome to apply at the latest 2023-07-26

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all