Postdoctoral Researcher in in vivo alpha-Synuclein studies

Do you want to contribute to top quality medical research?

The Svenningsson lab is a translational and multidisciplinary research group studying movement disorders, particularly Parkinson’s disease, and depression. We use cellular and animal models and analyze samples and biopsies from patients. Our goals are to understand the molecular mechanisms underlying disease states, and to identify novel biomarkers and medically relevant therapeutic targets. At the clinic, we do longitudinal studies on cohorts of patients with Parkinson’s disease and other movement disorders, assessing both motor and non-motor symptoms. We also perform clinical trials with novel pharmacological therapies.

Your mission

We are looking for a highly motivated postdoc, with an interest in translational Neuroscience and a strong background in animal models, neuroscience, pharmacology and/or behavioural studies to be involved in one or more projects investigating the molecular mechanisms underlying the alpha-synuclein-mediated neurodegeneration.

Find some of our recent papers here.

The postdoc will use transgenic animal models and viral vector approaches of alpha-synuclein and related molecules for studying alpha-synuclein spread and neurodegeneration caused.

We expect the successful candidate to be able to significantly contribute to the planning and management of their project(s), as well as to the writing of manuscripts and navigation of the peer-review process.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

Requirements:

PhD degree in relevant field (i.e. Neuroscience, biochemistry or molecular biology) – preferably graduated within the past 2 years
Lead author in at least 2 peer-reviewed publications
Documented experience in animal model research techniques (e.g. motor, cognitive and affective behavior tests)
Documented experience in animal surgery methods, such as stereotactic surgery, intracerebral injections, transcardial perfusions, etc.
Extensive experience in data analysis and data presentation
High level of self-motivation and independency
Work well with others in a team
Willingness to supervise or share experience with students
Very good command of written and spoken English

Desirable knowledge and experience:

Background in behavioural, pharmacological and/or biochemical studies of neuropathology of Parkinson’s disease or neurodegenerative disorders
Histology methods and Fluorescent and confocal Microscopy

What do we offer?

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.

Location: Solna

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
A complete list of publications
A summary of current work (no more than one page)

Welcome to apply at the latest October 1st, 2021.

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all!