Postdoctoral studies in (scholarship)

Do you want to contribute to top quality research in regenerative biology?

The Llorens laboratory offers a vibrant, stimulating and international environment. We are part of the Department of Cell and Molecular Biology at the Karolinska Institute in Stockholm, Sweden, one of the world’s leading medical universities. The lab is located in Biomedicum, one of Europe's largest laboratories with ultramodern facilities and rich opportunities for collaboration and career development.

Division

Our lab is interested in stimulating regeneration in the mammalian central nervous system (CNS). We use a multidisciplinary approach that involves stem cell biology, systems biology, computational biology, molecular engineering and mouse models of disease.

We are developing technologies for spatially resolved molecular profiling to support our research lines. This allows us to interrogate how cells ‘talk’ to each when tissue homeostasis is perturbed and identify the molecular programs underlying pathological cell states within their native neural tissue environment.

Recently, we have applied and developed cutting-edge single-cell and spatially resolved multiomics methods to uncover the mechanisms underlying cellular plasticity and tissue repair. In recent related work our lab has identified potential therapeutic targets for CNS repair after injury and during aging (Llorens-Bobadilla et al. Science 2020, Wu et al. Nat Neurosci 2025) and developed novel spatial epigenomics technologies (Llorens-Bobadilla et al. Nat Biotech 2023).

The current project focuses on the further development and application of spatially-resolved genomic technologies (transcriptomics, epigenomics, multiomics) to study the cellular and gene regulatory mechanisms underlying CNS pathology and repair.

Link to the the lab’s institutional website: https://ki.se/en/cmb/enric-llorens-group

Duties

We are seeking an ambitious, driven and enthusiastic postdoctoral fellow to develop and apply spatial genomics to address fundamental questions of tissue organization during CNS development and repair, as well as mechanisms of gene regulation underlying such processes.

Qualifications of the applicant

We are looking for highly motivated, independent, and self-driven candidates, with a strong track record and relevant experience during the PhD. The successful applicant should have a solid background in molecular biology techniques, method development and preferably bioinformatics. Experience in next-generation sequencing technologies and computational analysis, such as those related with spatial transcriptomics, epigenomics (e.g., ATAC- seq), and/or single-cell technologies is highly desirable.

An ability to independently carry out research projects documented in the publication record is required, as are good communication skills in spoken and written English. A demonstrated ability to develop and optimize molecular methods for spatial or single cell genome scale analyses and proficiency in at least one programming language (R, Python) for data analysis and will be considered an advantage.

Entry requirements

Postdoctoral scholarships may be established for foreign researchers who pursue their postdoctoral research in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.

A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.

To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Here, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Students and employees have free access to our modern gym facilities with trained staff on site.

Location:

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system.

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