Research Specialist in Mitochondrial Biology

Do you want to contribute to top quality medical research?

Applications are invited for the research specialist positions in the group of Joanna Rorbach at the Division of Molecular Metabolism, Karolinska Institutet, Stockholm.

The Division of Molecular Metabolism (http://ki.se/en/mbb/research-divisionof-molecular-metabolism, http://ki.se/en/mbb), is located in Biomedicum, Solna campus of Karolinska Institutet. The research at the division aims at understanding the regulation of mitochondrial function and the role of mitochondrial dysfunction in disease. The current research encompasses structural, biochemical and genetic studies of patients with inherited diseases as well as basic scientific approaches to understand the regulation of mtDNA expression and other aspects of mitochondrial metabolism.

The Division of Molecular Metabolism offers an outstanding research environment and a close interaction between basic science, clinical science and diagnostics at the Centre for Inherited Metabolic Diseases (CMMS) at Karolinska University Hospital, Stockholm, Sweden. Excellent access to the most advanced resources in structural, molecular and cell biology is available at the Institute and at the national core facilities at the Science for Life Laboratory (https://www.scilifelab.se).

Research background

Mitochondria are sub-cellular organelles essential for eukaryotic cell function, and their dysfunction has been implicated in a variety of hereditary diseases, ageing, cancer and immunity. The correct expression of mitochondrial DNA is essential for mitochondrial function. The aim of studies in Rorbach group is to identify the pathways and factors important to human diseases and improve our understanding of the fundamental mechanisms of mitochondrial function. We employ diverse model systems and multidisciplinary approaches to address these questions, including cryo-EM, high-throughput gene targeting, proteomics and RNASeq-based ribosome profiling. For future information, visit https://molmet.ki.se/rorbach

or contact Dr Joanna Rorbach, e-mail: Joanna.rorbach@ki.se.

Your mission

Enthusiastic and motivated applicants should have a strong background in structural biology, including cryoEM data collection and analysis.

Specific experience in mitochondrial biology is an advantage, given the nature of the research.

The successful applicant should be knowledgeable of biological advancements, demonstrate a promising publication record, and have a rigorous scientific approach.

The candidate should be able to work independently and interactively in a team and collaborative settings, as our research group collaborates with several international laboratories.

Eligibility requirements

To be eligible for employment as a Research Specialist, in addition to holding a Degree of Doctor, PhD, or having a foreign degree deemed equivalent to a Swedish doctoral degree, the applicant must have demonstrated research expertise as well as have documented research experience after defending their doctoral dissertation.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Here, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Biomedicum, Solna

Application

We prefer that Your application is written in English, but You can also apply in Swedish. An application must contain the following documents:  PhD certificate, resumé, qualifications and description of planned research, presented in accordance with Karolinska Institutet's qualifications portfolio.

Welcome to apply at the latest 2025-03-05

The application must be submitted through the Varbi recruitment system.

Permanent position is initiated by a six months trial period.

Want to make a difference? Join us and contribute to better health for all!