Research assistant position in Rheumatology research - Hiring in process/Finished, not possible to apply

Do you want to contribute to top quality medical research?

This comprehensive research project Joint Research Base for the Scientific Advancement of Plant-based Chinese Medicine (JRBCM) is based on the leading expertise in translational medical research at Center for Molecular Medicine at KI, and clinical and preclinical expertise with the founding partner Guangdong Provincial Hospital of Chinese Medicine. The main focus of JRBCM is to explore Chinese herbal drugs for development of novel drugs for inflammatory diseases. The herbal drugs will be subjected to detailed bioassay guided isolation of proteins, peptides and secondary metabolites using state of the art methods in pharmacognosy and pharmacology. Interesting discovered bioactivities will be subject to further characterization to elucidate mode of action and identify bioactive compounds.

Your mission

We are looking for a dedicated research assistant who will work to support ongoing JRBCM project focusing on screening plant-based compounds in a number of cell based assays. The isolation of active compounds will be performed in a step-wise manner applying relevant cell based assays for screening of activity combined with chemical assays. The work requires background in pharmacy and practical knowledge of molecular biology, cellular biology and protein biochemistry techniques. The work also requires previous hands on experience in handling mice.

Your profile

• MSc or higher in pharmacy
• Previous experience in experimental application of molecular and cellular biology techniques to the pharmacological studies
• Experience in cell culture
• Experience in handling mice
• Experience in documentation of research data in electronic lab books
• Strong language skills, including ability to speak and write English fluently
• Excellent interpersonal and communication skills

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Location

The position is located within the Department of Medicine, Solna. The department consists of twelve divisions and each division consists of several research groups. The position is located within the research group TRANSLATIONAL MEDICAL RESEARCH IN INFLAMMATORY DISEASES. The group is led by Professor Per-Johan Jakobsson and conducts research at the Rheumatology Division, Centrum of Molecular Medicine. The group is aiming to explore targets and pathways in rheumatic diseases driven by inflammation using a pharmacological approach. We focus on the arachidonic acid cascade, development of mPGES-1 inhibitors and epigenetic modulators. We also investigate biomarkers in rheumatic diseases and the pathophysiological role of associated antigens and autoantibodies. We are equipped for eicosanoid research, patient derived cell assays and a platform dedicated to protein expression and antibody generation. We perform proteomics, lipid metabolomics and cytokine profiling; often focused on the effects of prototype drugs targeting under-explored areas of human diseases driven by inflammation https://ki.se/en/meds/research-group-per-johan-jakobsson

Application

The application is to be submitted through the Varbi recruitment system.  

Permanent position is initiated by a six months trial period.

Want to make a difference? Join us and contribute to better health for all