Researcher in molecular neurophysiology - Hiring in process/Finished, not possible to apply

Division

Research in the molecular neurophysiology laboratory aims to identify neuronal alterations in models of Parkinson’s disease, focusing on glutamatergic synapses in the basal ganglia. Our research investigates if the functions of the NMDA type of glutamate receptors, and their subunit composition, are altered in different neuronal populations of the basal ganglia in experimental Parkinsonism. Another important goal of our research is to increase our understanding of the mechanisms that lead to the rapid and long-lasting antidepressant action of ketamine.

Duties

The senior researcher will identify synaptic alterations and dysfunctions in synaptic plasticity in the basal ganglia of different animal models of Parkinson’s disease. The researcher will also examine how, and by which cellular and molecular mechanisms, a low dose of ketamine modifies synaptic transmission and plasticity in the brain reward circuit. The methods used include brain slice electrophysiology and electrochemistry in combination with pharmacological tools, Western blotting, histochemistry and behavioral analysis. The selected researcher will also contribute to undergraduate and graduate education.

Entry requirements

A person is eligible to be appointed Senior Researcher if he or she has been awarded a Degree of Doctor or has achieved the corresponding scientific competence, as well as documented research after publicly defending his or her doctoral thesis corresponding to qualification as Assistant professor.

We are seeking a highly motivated, enthusiastic and creative person. An absolute requirement is a strong interest and expertise in neurophysiology, biochemistry and histochemistry. The applicant must have excellent knowledge of the field of Parkinson’s disease and glutamate-based antidepressant therapies. Training in medicine and a M.D. degree are strong advantages. Emphasis will be placed on personal ability and previous research experience. In addition to this, the applicant must display pedagogical proficiency and excellent command of the English language.

Bases os assessment

We stress research expertise when assessing applicants.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Location: Solna

Application

An application must contain the following documents in English: Resumé, qualifications and description of planned research, presented in accordance with Karolinska Institutet's qualifications portfolio.

Welcome to apply at the latest 20 november

The application is to be submitted through the Varbi recruitment system.  

Permanent position are initiated by a six months trial period

Want to make a difference? Join us and contribute to better health for all