Postdoctoral Researcher in systems immunology and organoid culturing

Do you want to contribute to top quality medical research?

The Thålin research group opens a position for a skilled and ambitious bioinformatician with a passion for discovery and translational immunology. This position is part of an ERC funded cutting-edge research initiative aimed at understanding and leveraging the structure-function relationships of mucosal IgA antibodies to inform the design of next-generation vaccines and therapeutic antibodies. Leveraging our globally unique biobank of human nasal secretions and expanding on our molecular-level characterization of mucosal IgA, we will test recombinant secretory IgA candidates for their ability to safely block respiratory infections through cell-based assays, affinity liquid chromatography–mass spectrometry, omics analysis and by leveraging human stem cell-derived nasal and lung organoids. This is an exciting opportunity for a talented and ambitious scientist to contribute not only to scientific discovery but also to the strategic development of a rapidly expanding research group.

Your mission

You will work with our existing data set as well as ongoing application and integration of multi-omics approaches, including proteomics and transcriptomics. The position will include close collaborative work with team members across immunology, structural biology, and bioinformatics and within the international network, driving your own projects forward. In addition to leading experimental work, you will play an active role in shaping the strategic direction of the lab. This includes contributing to the scientific vision and strategic planning of ongoing and future projects, assisting in grant application writing, organizing and participating in team meetings, workshops, and collaborations and mentoring of junior researchers.

Your profile
We are looking for a highly motivated and dedicated postdoctoral fellow with the following competencies and experience.
Essential experience and skills:

• You are a senior researcher with a PhD in life sciences
• You have a strong background in antibody biology, mucosal immunology, or biotechnology
• You have a strong background in mass spectrometry, omics analysis and recombinant protein expression and engineering
• You have a strong interest in and experience of supervising students
• You have excellent organizational, planning and record-keeping skills
• You have an open and service-minded attitude
• You have excellent teamwork and communication skills
• You have excellent English skills, written and spoken 

To be eligible for employment as a postdoctor, a PhD or a foreign degree deemed to be equivalent to a Swedish PhD is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. Completion of your doctoral degree within the last three years is considered an advantage. If there are special reasons, your degree may have been completed earlier.

What do we offer?

The position will be in the Thålin group at the Department of Clinical Sciences, Danderyd Hospital which offers an inspiring and supportive research environment. The department is growing and consists of research nurses, biomedical analysts, senior researchers, post docs, and Ph.D students as well as administrative personnel. The project is cutting-edge within a rapidly moving research field and conducted in close collaboration with world-leading international research groups at Leiden University Medical Center (LUMC), Uppsala University and KTH.
Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Terms and conditions

We offer a postdoctoral fellow for an initial appointment of one year, with a possible extension for up to 1 additional year.

Location: Danderyd

Department of Clinical Sciences, Danderyd Hospital

Thålin research group

Application

An employment application must contain the following documents in English or Swedish:

• PhD certificate
• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

Welcome to apply at the latest 2025-06-18

The application is to be submitted through the Varbi recruitment system.

Permanent position is initiated by a six months trial period.

Want to make a difference? Join us and contribute to better health for all!