Postdoctoral Researcher in Neuroscience with focus on motivated behaviours

Do you want to contribute to top quality medical research?

The Meletis laboratory, in the Department of Neuroscience, has an open position for a postdoctoral fellow to investigate the function of neuron subtypes during motivated behavior and decision-making, including circuit dysfunction in mouse models of stress and mood disorders. The project will address the in vivo role of molecularly defined neuron subtypes in the basal ganglia, hypothalamus, and the lateral habenula.

Your mission

The research will be based on the functional investigation of the role of neurons and circuits in motivated behaviors through a number of advanced circuit approaches to target, record and manipulate molecularly defined neurons. The project will involve the use and development of genetically modified mice to target neuron subtypes using in vivo optogenetics and behavioral paradigms (freely moving and head-fixed) to define the contribution of specific circuits to motivated and aversive behavior. The project will benefit from ongoing projects that have established the identity and connectivity of neurons in candidate circuits based on single cell RNA-seq and monosynaptic rabies tracing.

Successful applicants will have the opportunity to work in a stimulating and collaborative environment with state-of-the-art infrastructure.

We expect applicants to have a strong determination to reveal the role of neurons and circuits to behavior, with extensive experience and interest in behavior, electrophysiology and/or in vivo imaging. Extensive knowledge in methods to quantify neuron activity, statistics and programming, are required.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

This is a fixed-term position for 2 years.

Location: Solna

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Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work A complete list of publications A summary of current work (no more than one page)

Welcome to apply at the latest November 18th, 2022.

The application is to be submitted through the Varbi recruitment system.

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