Research Specialist in process development for Advance Therapy Medicinal Products (ATMPs)

Do you want to contribute to top quality medical research?

The Pre-GMP core facility at ANA Futura

The Pre-GMP facility was created within a Centre for Advanced Medical Products (CAMP) project to support researchers and biotech industries to successfully overcome road blocks in the process of developing Advanced Therapy Medicinal Products (ATMPs). The Pre-GMP facility works in close collaboration with the GMP facility Vecura present at the Karolinska University Hospital. The two facilities are harmonized to provide a smooth transition of ATMPs projects from process development to GMP production.

The goals of the Pre-GMP facility are to provide the technical support and resources to researchers with specific focus on:

Make research projects ready for transition to GMP production
Develop and validate SOPs
Test new equipment
Train and educate staff and students

Your mission

Within the pre-GMP facility the successful applicant will have the opportunity to work in a variety of projects related to ATMPs, some examples will be production of HQ plasmids, production of viral vectors, genetic modification and expansion of CAR- and TCR-T cells and NK cells.

In particular the successful candidate will be required to:

Develop and validate specific SOPs in collaboration with the PI for each specific project
Provide technical support and training on specific equipment to the facility users
Contribute to the facility management by maintaining a good record of the usage of the instruments and consumables

Eligibility requirements

To be eligible for employment as a Research Specialist, in addition to holding a Degree of Doctor, PhD, or having equivalent scientific expertise, the applicant must have demonstrated research expertise as well as have documented research experience after defending their doctoral dissertation.

The ideal candidate for this position is independent, practical, organized and detailed oriented. Candidates should be highly-motivated, creative, have strong communication skills as well as an excellent track record and extensive knowledge in process development and validation for cell therapy, gene therapy and other ATMPs.

Documented experience and independent work in the field of ATMP manufacturing, cell culture, genetic modification of lymphocytes by viral and non-viral vectors, advanced knowledge of molecular biology and T cells biology is all required.

Documented theoretical and practical GMP training is mandatory.

The candidate must be skilled in using standard information technologies for biomedical research purposes. Fluency in English and skills in scientific writing are mandatory. High level oral and written presentation skills are critical for these positions.

We are looking for a researcher who has a strong work ethic, high integrity and be aware of the multicultural setting they are going to be located at. Personal suitability will be a strong selection criterion.

Assessment criteria

It is particularly meritorious that the applicant has shown

Hands-on experience with closed and automated devices for cell processing
Previous experience with process development for ATMPs

It is meritorious that the applicant has shown

Previous experience of working in a core-facility

After an overall assessment of the expertise and merits of the applicants in relation to the subject area, Karolinska Institutet will determine which of them has the best potential to contribute to a positive development of the activities at KI.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Location: Flemingsberg

https://staff.ki.se/core-facility-for-campus-flemingsberg-pre-gmp

Application

We prefer that Your application is written in English, but You can also apply in Swedish. An application must contain the following documents: Resumé, qualifications and description of planned research, presented in accordance with Karolinska Institutet's qualifications portfolio.

Welcome to apply at the latest 18 August.

The application must be submitted through the Varbi recruitment system.

Permanent position is initiated by a six months trial period.

Want to make a difference? Join us and contribute to better health for all