Postdoctoral Researcher in Receptor Pharmacology

Do you want to contribute to better health for all?

In the division “Receptor Biology & Signaling” headed by Prof Gunnar Schulte, G protein-coupled receptors and particularly Class F receptors are in focus. The work aims to better understand how ligands interact with Class F receptors, how conformational changes are established to activate the receptors and consequently to initiate interaction and activation of intracellular signaling components. Functional selectivity of Class F receptors towards heterotrimeric G proteins or other pathways are analyzed with the hope to exploit the novel knowledge therapeutically.
For more information: https://ki.se/en/fyfa/schulte-lab

Your mission

The research project is aiming to understand underlying molecular details of Class F receptor activation for future drug development. The highly motivated candidate, with a strong background in GPCR pharmacology, is expected to drive research project, technical development and concept development from idea to publication. The candidate’s broad expertise in wet laboratory and in silico experiments is expected to serve as a resource for the research team. The candidate will participate in supervision of masters and PhD students. In addition to lab work, the applicant is expected to take an active, constructive and developing part in lab management.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

The applicant should have a profound background in biochemistry, molecular biology, cell biology with emphasis on GPCR pharmacology. Solid experience in cell culture, resonance energy transfer-based (FRET/BRET) techniques, cloning, amber codon orthogonal labeling procedures and protein biochemistry, are required. Documented experience (previous high quality publications) with GPCR pharmacology and protein biochemistry is a requirement. Experience with software such as GraphPad Prism, PyMOL, GROMACS, VMD is advantageous for selection.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Location: Solna Campus

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
A complete list of publications
A summary of current work (no more than one page)

Welcome to apply!

The application is to be submitted through the Varbi recruitment system.

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